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Home Epigenetics Cell cycle Apoptosis LY293111 - ≥98%, high purity , Peroxisome proliferator-activated receptor gamma agonist, CAS No.161172-51-6, Peroxisome proliferator-activated receptor gamma agonist
LY293111 - ≥98%, high purity , Peroxisome proliferator-activated receptor gamma agonist, CAS No.161172-51-6, Peroxisome proliferator-activated receptor gamma agonist
Basic Description Synonyms Etalocib|161172-51-6|LY293111|Etalocib sodium|VML295|Etalocib [USAN]|LY 293111|LY-293111|VML 295|THY6RIW44R|2-[3-[3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxyphenoxy]propoxy]-2-propylphenoxy]benzoic acid|LY-193111|CHEMBL329123|Benzoic acid, 2-[3-[3-[(5-ethyl-4 Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms Etalocib (LY293111), an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Peroxisome proliferator-activated receptor gamma agonist Product Description Application：
LY293111 is a leukotriene receptor antagonist and protect neurons from the sPLA2-IB-induced neuronal cell death independently of blocking their receptors.
Names and Identifiers IUPAC Name 2-[3-[3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxyphenoxy]propoxy]-2-propylphenoxy]benzoic acid INCHI InChI=1S/C33H33FO6/c1-3-9-25-29(12-7-13-30(25)40-31-11-6-5-10-26(31)33(36)37)38-18-8-19-39-32-21-28(35)27(20-22(32)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37) InChi Key YFIZRWPXUYFCSN-UHFFFAOYSA-N Canonical SMILES CCCC1=C(C=CC=C1OC2=CC=CC=C2C(=O)O)OCCCOC3=CC(=C(C=C3CC)C4=CC=C(C=C4)F)O Isomeric SMILES CCCC1=C(C=CC=C1OC2=CC=CC=C2C(=O)O)OCCCOC3=CC(=C(C=C3CC)C4=CC=C(C=C4)F)O PubChem CID 177941 UN Number 1231 Packing Group II Molecular Weight 544.6
Chemical and Physical Properties Solubility MF: 30 mg/ml DMSO: 30 mg/ml Ethanol: 30 mg/ml Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml Boil Point(°C) 57° C
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G2220688