LY294002 - ≥98%, high purity , CAS No.154447-36-6

Item Number

L124970

• Synonyms: 154447-36-6|LY294002|LY 294002|2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|LY-294002|2-morpholino-8-phenyl-4H-chromen-4-one|2-morpholin-4-yl-8-phenyl-4H-chromen-4-one|2-morpholin-4-yl-8-phenylchromen-4-one|2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: LY294002 is a potent inhibitor of PI 3-kinase, a protein in the phosphoinositide 3-kinase family of intercellular signal regulating enzymes. This compound is selective for PI 3-kinase p110 β (PI 3-Kβ) and PI 3-kinase p110 α (PI 3-Kα), although it will inh
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.
A potent blocker of PI 3-kinase/Akt signaling.