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LY395756 , CAS No.L611665, Agonist of mGlu 2 receptor;Antagonist of mGlu 3 receptor

  • Moligand™
Item Number
L611665
Grouped product items
SKUSizeAvailabilityPrice Qty
L611665-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
L611665-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
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mGlu2 receptor Agonist mGlu3 receptor Antagonist

Basic Description

Synonyms(±)-LY 395756;LY 395756;LY-395756;LY39
Specifications & PurityMoligand™
GradeMoligand™
Action TypeAGONIST, ANTAGONIST
Mechanism of actionAgonist of mGlu 2 receptor;Antagonist of mGlu 3 receptor

Associated Targets

GRM2 Tchem Metabotropic glutamate receptor 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM8 Tchem Metabotropic glutamate receptor 8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM3 Tchem Metabotropic glutamate receptor 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM6 Tchem Metabotropic glutamate receptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

INCHI InChI=1S/C9H13NO4/c1-3-2-9(10,8(13)14)6-4(3)5(6)7(11)12/h3-6H,2,10H2,1H3,(H,11,12)(H,13,14)/t3-,4+,5+,6+,9+/m1/s1
InChi Key BQVZICWQBFTOJX-QNDZYWSYSA-N
Canonical SMILES C[C@@H]1C[C@@]([C@H]2[C@@H]1[C@@H]2C(=O)O)(N)C(=O)O
Isomeric SMILES C[C@@H]1C[C@]([C@H]2[C@@H]1[C@@H]2C(=O)O)(C(=O)O)N
PubChem CID 11310142

Certificates

Certificate of Analysis(COA)

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Related Documents

 SDS

 Specification Sheet

References

1. Li ML, Yang SS, Xing B, Ferguson BR, Gulchina Y, Li YC, Li F, Hu XQ, Gao WJ.  (2015)  LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment..  Exp Neurol,  273  (3): (190-201).  [PMID:26341392]

Solution Calculators

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