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MADH7/SMAD7 Antibody - Primary antibody, specific to SMAD7, Rabbit IgG

  • Validated
  • 1.0 mg/mL
Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human MADH7/SMAD7 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Goat,Human,Mouse,Rat,Sheep
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab113970
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab113970-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab113970-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab113970-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab113970-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

pAb; Rabbit anti Human MADH7/SMAD7 Antibody; WB; Unconjugated

Basic Description

Product NameMADH7/SMAD7 Antibody - Primary antibody, specific to SMAD7, Rabbit IgG
Specifications & PurityValidated, 1.0 mg/mL
Host speciesRabbit
SpecificitySMAD7
ImmunogenA synthetic peptide derived from human SMAD7.
Positive ControlWB: Mouse lung, Jurkat, NIH/3T3 and C6 lysates.
ConjugationUnconjugated
GradeValidated
Product Description

Rabbit anti Human MADH7/SMAD7 Antibody, Polyclonal, could be used for WB and so on.
Application
WB: 1/500-1/2000
Protein Function
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodImmunogen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets

SMAD7 Tbio Mothers against decapentaplegic homolog 7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/2000

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators