MAK683-CH2CH2COOH hydrochloride - 97%, high purity , CAS No.M659034

Item Number

M659034

Grouped product items
SKU	Size	Availability	Price	Qty
M659034-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$510.90
M659034-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$820.90

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Basic Description

Specifications & Purity	≥97%
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Product Description	MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 ( HY-130614 ) and PROTAC EED degrader-2 ( HY-130615 ). Appearance:Solid In Vitro:MAK683-CH2CH2COOH inhibits Karpas422 cells with a GI 50 of 14 nM for 14 days treatment. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 ( HY-130614 ) and PROTAC EED degrader-2 ( HY-130615 ).

Canonical SMILES

[H]Cl.FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=C(C)N=C(CCC(O)=O)C=C4)C5=NN=CN35

Molecular Weight

484.91

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Basic Description