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Mal-amido-PEG2-Val-Cit-PAB-PNP - 98%, high purity , CAS No.2112738-13-1

Item Number

M596379

Grouped product items
SKU	Size	Availability	Price
M596379-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,621.90
M596379-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,671.90
M596379-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,801.90

Val-Cit

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Basic Description

Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.

Canonical SMILES	CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCOCCOCCNC(=O)CCN3C(=O)C=CC3=O
Isomeric SMILES	CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCOCCOCCNC(=O)CCN3C(=O)C=CC3=O
PubChem CID	129009582
Molecular Weight	854.9

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Solubility	Solubility in DMSO, DCM, DMF

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