Maleimide-poly(ethylene glycol)-b-poly(ε-caprolactone) - PEG average Mₙ 5000, PCL average Mₙ 5000, high purity

1 Citations
  • PEG average Mₙ 5000, PCL average Mₙ 5000
Item Number
M475619
Grouped product items
SKUSizeAvailabilityPrice Qty
M475619-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,145.90

Basic Description

Specifications & PurityPEG average Mₙ 5000, PCL average Mₙ 5000
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Description

Maleimide-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block.These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

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Related Documents

Citations of This Product

1. Jian Jin, Bowen Sui, Jingxin Gou, Jingshuo Liu, Xing Tang, Hui Xu, Yu Zhang, Xiangqun Jin,.  (2014-11-12)  PSMA ligand conjugated PCL-PEG polymeric micelles targeted to prostate cancer cells..  PloS one,  ((11)): ( e112200-e112200 ).  [PMID:25386942]

References

1. Jian Jin, Bowen Sui, Jingxin Gou, Jingshuo Liu, Xing Tang, Hui Xu, Yu Zhang, Xiangqun Jin,.  (2014-11-12)  PSMA ligand conjugated PCL-PEG polymeric micelles targeted to prostate cancer cells..  PloS one,  ((11)): ( e112200-e112200 ).  [PMID:25386942]

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