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Manelimab (anti-PD-L1) - Primary antibody, specific to CD274, Human IgG1

  • Azide Free
  • Carrier Free
  • ExactAb™
  • Low Endotoxin
  • Recombinant
  • Validated
  • ≥95%(SDS-PAGE&SEC)
  • Lot by Lot
Features and benefits
  • Short Overview:

    Purity>95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

  • Species reactivity(Reacts with): Cynomolgus monkey,Human
  • Isotype: Human IgG1
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
Item Number
Ab182878
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab182878-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab182878-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab182878-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab182878-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product NameManelimab (anti-PD-L1) - Primary antibody, specific to CD274, Human IgG1
Specifications & PurityCarrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC), Lot by Lot
SpecificityCD274
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Manelimab (anti-PD-L1) is a monoclonal antibody that inhibits programmed death-ligand 1 (PD-L1).
Purity>95% (SDS-PAGE&SEC)
Endotoxin Level < 0.01EU/μg

Product Properties

IsotypeHuman IgG1
Light Chain Typelambda
SDS-PAGE26.8 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 196.5 kDa, under non-reducing conditions.
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -80°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS2168561-26-8

Images

Manelimab (anti-PD-L1) (Ab182878) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-L1 (red) with Manelimab (anti-PD-L1) (Ab182878) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Manelimab (anti-PD-L1) (Ab182878) - ELISA
Immobilized Recombinant Human PD-L1 protein (rp169666) at 1.0 μg/mL can bind Manelimab (anti-PD-L1) (Ab182878) with the EC50 of 51.00 ng/mL.

Manelimab (anti-PD-L1) (Ab182878) - SEC
The purity of Manelimab (anti-PD-L1) (Ab182878) is more than 95% verified by HPLC.

Associated Targets

CD274 Tclin Programmed cell death 1 ligand 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708328Certificate of AnalysisJul 16, 2024 Ab182878
ZJ24F0708327Certificate of AnalysisJul 16, 2024 Ab182878
ZJ24F0708326Certificate of AnalysisJul 16, 2024 Ab182878

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