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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M342001-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $49.90 | |
M342001-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
M342001-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $189.90 | |
M342001-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $329.90 | |
M342001-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $489.90 |
Synonyms | Marein|535-96-6|Okanin-4'-O-glucoside|CHEMBL490510|CY787E65J4|(E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one|2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-(beta-D-gluco |
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Specifications & Purity | ≥98% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 µM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects |
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IUPAC Name | (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one |
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INCHI | InChI=1S/C21H22O11/c22-8-15-18(28)19(29)20(30)21(32-15)31-14-6-3-10(16(26)17(14)27)11(23)4-1-9-2-5-12(24)13(25)7-9/h1-7,15,18-22,24-30H,8H2/b4-1+/t15-,18-,19+,20-,21-/m1/s1 |
InChi Key | XGEYXJDOVMEJNG-HTFDPZBKSA-N |
Canonical SMILES | O=C(C1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C(O)=C1O)/C=C/C3=CC=C(O)C(O)=C3 |
Isomeric SMILES | C1=CC(=C(C=C1/C=C/C(=O)C2=C(C(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O)O |
PubChem CID | 6441269 |
Molecular Weight | 450.39 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2416268 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416269 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416270 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416271 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416272 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416273 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416274 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416275 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416276 | Certificate of Analysis | May 07, 2024 | M342001 |
H2416277 | Certificate of Analysis | May 07, 2024 | M342001 |
Sensitivity | Light sensitive |
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Melt Point(°C) | 197-202° C |