We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency.Click herefor more information.1-(3,5-bis(trifluoromethyl)phenyl)-3-(2-(difluoroboryl)phenyl)urea is a robust and user-friendly white solid capable of being stored on the benchtop indefinitely. The strategic incoporation of the difluoroboryl substituent renders this the most acidic urea catalyst reported to date (pKa(DMSO) = 7.5). This difluorboronate urea benefits from enhanced reaction rates and yields when compared to traditional urea catalysts. It also enables reactions that are inaccessible with conventional urea catalysis.
1.Andrea M Hardman, Sonia S So, Anita E Mattson,. (2013-08-03) Urea-catalyzed construction of oxazinanes.. Organic & biomolecular chemistry, 11 ((35)):( 5793-5797 ). [PMID:23907178]
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