Maytansine - 99%, high purity , CAS No.35846-53-8

Item Number

M647545

Grouped product items
SKU	Size	Availability	Price
M647545-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$75.90
M647545-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$130.90
M647545-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$290.90

Alkaloids Other Alkaloids

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Basic Description

Synonyms	MAYTANSINE\|Maitansine\|Maitansina\|Maytansine [USAN]\|Maitansinum\|NSC-153858\|35846-53-8\|NSC 153858\|Maitansine [INN]\|Maytansin\|CHEBI:6701\|Maytansine (USAN)\|N-Acetyl-N-methyl-L-alanine(1S-(1R,2S,3R,5R,6R,16E,18E,20S,21R*))-11-chloro-21-hydroxy-12,20-dime
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations. In Vitro Maytansine, at 6x10 -8 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Names and Identifiers

IUPAC Name	[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[acetyl(methyl)amino]propanoate
INCHI	InChI=1S/C34H46ClN3O10/c1-18-11-10-12-26(45-9)34(43)17-25(46-32(42)36-34)19(2)30-33(5,48-30)27(47-31(41)20(3)37(6)21(4)39)16-28(40)38(7)23-14-22(13-18)15-24(44-8)29(23)35/h10-12,14-15,19-20,25-27,30,43H,13,16-17H2,1-9H3,(H,36,42)/b12-10+,18-11+/t19-,20+,25+,26-,27+,30+,33+,34+/m1/s1
InChi Key	WKPWGQKGSOKKOO-RSFHAFMBSA-N
Canonical SMILES	CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)C)C)C)OC)(NC(=O)O2)O
Isomeric SMILES	C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)C)C)\C)OC)(NC(=O)O2)O
PubChem CID	5281828
Molecular Weight	692.2

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Basic Description