Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab182698-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab182698-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $349.90 | |
| Ab182698-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $869.90 | |
| Ab182698-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,389.90 |
Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | MEDI-5117 (anti-IL-6) - Primary antibody, specific to IL6, Human IgG1 |
|---|---|
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Low Endotoxin, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | IL6 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interleukin-6 inhibitor |
| Product Description |
MEDI-5117 (anti-IL-6) is a human monoclonal antibody against Interleukin-6 (IL-6), a pleiotropic cytokine with immune regulation, inflammation, and oncogenesis. It has the potential to treat rheumatoid arthritis (RA). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.14 kDa |
| Purification Method | Protein A purified |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
MEDI-5117 (anti-IL-6) (Ab182698) - ELISA
Immobilized Recombinant Human IL-6 protein (rp156005) at 1.0 μg/mL can bind MEDI-5117 (anti-IL-6) (Ab182698) with the EC50 of 13.84 ng/mL.
MEDI-5117 (anti-IL-6) (Ab182698) - SEC
The purity of MEDI-5117 (anti-IL-6) (Ab182698) is more than 95% verified by HPLC.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0708650 | Certificate of Analysis | Jul 24, 2024 | Ab182698 |
| ZJ24F0708649 | Certificate of Analysis | Jul 24, 2024 | Ab182698 |
| ZJ24F0708648 | Certificate of Analysis | Jul 24, 2024 | Ab182698 |
