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Merbarone - ≥98%, high purity , CAS No.97534-21-9

≥98%

CAS#: 97534-21-9
Formula: C₁₁H₉N₃O₃S
Molecular Weight: 263.27
PubChem CID: 4990817

Item Number

M345212

Grouped product items
SKU	Size	Availability	Price
M345212-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$52.90
M345212-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$80.90
M345212-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$152.90
M345212-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$437.90

View related series

Cell Cycle/DNA Damage Topoisomerase

Basic Description

Synonyms	merbarone\|97534-21-9\|NSC 336628\|YWB9IF596V\|CHEMBL1765797\|5-Pyrimidinecarboxamide, hexahydro-4,6-dioxo-N-phenyl-2-thioxo-\|5-(N-Phenylcarboxamido)-2-thiobarbituric acid\|CCRIS 8215\|5-(N-Phenylcarbamoyl)-2-thiobarbituric acid\|UNII-YWB9IF596V\|US9428466, Merbar
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Merbarone (NSC 336628) is an orally active inhibitor of topoisomerase II. Merbarone acts primarily by blocking topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes. Merbarone is an anticancer agent.

Associated Targets

SLC22A12 Tclin Solute carrier family 22 member 12 0 Activities

Discover Target: SLC22A12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TOP2A Tclin DNA topoisomerase 2-alpha 0 Activities

Discover Target: TOP2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities

Discover Target: XDH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	4,6-dioxo-N-phenyl-2-sulfanylidene-1,3-diazinane-5-carboxamide
INCHI	InChI=1S/C11H9N3O3S/c15-8(12-6-4-2-1-3-5-6)7-9(16)13-11(18)14-10(7)17/h1-5,7H,(H,12,15)(H2,13,14,16,17,18)
InChi Key	JARCFMKMOFFIGZ-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)NC(=O)C2C(=O)NC(=S)NC2=O
Isomeric SMILES	C1=CC=C(C=C1)NC(=O)C2C(=O)NC(=S)NC2=O
WGK Germany	3
RTECS	UV7714625
PubChem CID	4990817
Molecular Weight	263.27

Solubility

Soluble in DMSO (>5 mg/ml).

Refractive Index

n20D1.69 (Predicted)

Boil Point(°C)

627.51° C at 760 mmHg (Predicted)

Melt Point(°C)

272.16° C

WGK Germany

RTECS

UV7714625

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Merbarone - ≥98%, high purity , CAS No.97534-21-9

Basic Description

Associated Targets

SLC22A12 Tclin Solute carrier family 22 member 12 0 Activities

HDAC6 Tclin Histone deacetylase 6 0 Activities

TOP2A Tclin DNA topoisomerase 2-alpha 0 Activities

XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

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Dilution Calculator

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