Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
M163013-5g | 5g | In stock | $9.90 | |
M163013-25g | 25g | In stock | $32.90 | |
M163013-100g | 100g | In stock | $89.90 | |
M163013-500g | 500g | In stock | $359.90 |
Synonyms | 4432-31-9|4-Morpholineethanesulfonic acid|2-Morpholinoethanesulfonic acid|2-(N-Morpholino)ethanesulfonic acid|MES|4-Morpholinethanesulfonic acid|2-Morpholinoethanesulphonic acid|2-(4-Morpholinyl)ethanesulfonic acid|2-morpholin-4-ylethanesulfonic acid|Morp |
---|---|
Specifications & Purity | ≥99.5%(T) |
Storage Temp | Room temperature |
Shipped In | Normal |
Product Description | useful pH range 5.5 - 6.7 pKa 6.1 product description: MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. application: MES has been used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles. MES has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | 2-morpholin-4-ylethanesulfonic acid |
---|---|
INCHI | InChI=1S/C6H13NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h1-6H2,(H,8,9,10) |
InChi Key | SXGZJKUKBWWHRA-UHFFFAOYSA-N |
Canonical SMILES | C1COCCN1CCS(=O)(=O)O |
Isomeric SMILES | C1COCCN1CCS(=O)(=O)O |
WGK Germany | 1 |
RTECS | QE3479500 |
PubChem CID | 78165 |
Molecular Weight | 195.24 |
Beilstein | 141319 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
I2406300 | Certificate of Analysis | Aug 26, 2024 | M163013 |
I2406283 | Certificate of Analysis | Aug 26, 2024 | M163013 |
E2421467 | Certificate of Analysis | May 11, 2024 | M163013 |
E2421427 | Certificate of Analysis | May 11, 2024 | M163013 |
E2421260 | Certificate of Analysis | May 11, 2024 | M163013 |
B2422257 | Certificate of Analysis | Jan 26, 2024 | M163013 |
B2422258 | Certificate of Analysis | Jan 26, 2024 | M163013 |
B2422259 | Certificate of Analysis | Jan 26, 2024 | M163013 |
B2422260 | Certificate of Analysis | Jan 26, 2024 | M163013 |
K2302054 | Certificate of Analysis | Oct 13, 2023 | M163013 |
J2311068 | Certificate of Analysis | Oct 13, 2023 | M163013 |
D23031099 | Certificate of Analysis | Oct 28, 2022 | M163013 |
K2209727 | Certificate of Analysis | Oct 28, 2022 | M163013 |
B2311221 | Certificate of Analysis | Oct 28, 2022 | M163013 |
B2310742 | Certificate of Analysis | Oct 28, 2022 | M163013 |
B2310713 | Certificate of Analysis | Oct 28, 2022 | M163013 |
K2209726 | Certificate of Analysis | Oct 28, 2022 | M163013 |
K2209725 | Certificate of Analysis | Oct 28, 2022 | M163013 |
K2209724 | Certificate of Analysis | Oct 28, 2022 | M163013 |
D23031098 | Certificate of Analysis | Oct 28, 2022 | M163013 |
B2310702 | Certificate of Analysis | Oct 28, 2022 | M163013 |
I2212112 | Certificate of Analysis | Aug 24, 2022 | M163013 |
I2212111 | Certificate of Analysis | Aug 24, 2022 | M163013 |
I2212108 | Certificate of Analysis | Aug 24, 2022 | M163013 |
I2212107 | Certificate of Analysis | Aug 24, 2022 | M163013 |
E2227100 | Certificate of Analysis | Jun 01, 2022 | M163013 |
A2219013 | Certificate of Analysis | Dec 30, 2021 | M163013 |
A2219012 | Certificate of Analysis | Dec 30, 2021 | M163013 |
A2218543 | Certificate of Analysis | Dec 30, 2021 | M163013 |
Melt Point(°C) | 316°C |
---|
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. |
WGK Germany | 1 |
RTECS | QE3479500 |
Starting at $11.90
Starting at $29.90
Starting at $261.90
Starting at $23.90
Starting at $93.90
Starting at $36.90
Starting at $35.90
Starting at $101.90
1. C L Mackowiak,P R Grossl,B G Bugbee. (2002-03-12) Beneficial effects of humic acid on micronutrient availability to wheat.. Soil Science Society of America journal. Soil Science Society of America, 65 ((6)): (1744-1750). [PMID:11885604] |
2. Lars Haag,Henrik Garoff,Li Xing,Lena Hammar,Sin-Tau Kan,R Holland Cheng. (2002-08-29) Acid-induced movements in the glycoprotein shell of an alphavirus turn the spikes into membrane fusion mode.. The EMBO journal, 21 ((17)): (4402-4410). [PMID:12198142] |
3. Tsuyoshi Shirai,Yuuka Matsui,Clara Shionyu-Mitsuyama,Takashi Yamane,Hisao Kamiya,Chihiro Ishii,Tomohisa Ogawa,Koji Muramoto. (2002-09-11) Crystal structure of a conger eel galectin (congerin II) at 1.45A resolution: implication for the accelerated evolution of a new ligand-binding site following gene duplication.. Journal of molecular biology, 321 ((5)): (879-889). [PMID:12206768] |
4. Yue-Hua Dou,Ning Bao,Jing-Juan Xu,Hong-Yuan Chen. (2002-11-02) A dynamically modified microfluidic poly(dimethylsiloxane) chip with electrochemical detection for biological analysis.. Electrophoresis, 23 ((20)): (3558-3566). [PMID:12412125] |
5. Jin-Peng Sun,Alexander A Fedorov,Seung-Yub Lee,Xiao-Ling Guo,Kui Shen,David S Lawrence,Steven C Almo,Zhong-Yin Zhang. (2003-01-28) Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.. The Journal of biological chemistry, 278 ((14)): (12406-12414). [PMID:12547827] |
6. Pasi S Vuorinen,Matti Jussila,Heli Sirén,Sami Palonen,Marja-Liisa Riekkola. (2003-04-11) Integration of a contactless conductivity detector into a commercial capillary cassette. Detection of inorganic cations and catecholamines.. Journal of chromatography. A, 990 ((1-2)): (45-52). [PMID:12685582] |
7. Ekta G Ahuja,Dimitri V Mavrodi,Linda S Thomashow,Wulf Blankenfeldt. (2004-05-26) Overexpression, purification and crystallization of PhzA, the first enzyme of the phenazine biosynthesis pathway of Pseudomonas fluorescens 2-79.. Acta crystallographica. Section D, Biological crystallography, 60 ((Pt 6)): (1129-1131). [PMID:15159577] |
8. C Jacyn Baker,Norton M Mock,Daniel P Roberts,Kenneth L Deahl,Cathleen J Hapeman,Walter F Schmidt,Jan Kochansky. (2007-09-26) Interference by Mes [2-(4-morpholino)ethanesulfonic acid] and related buffers with phenolic oxidation by peroxidase.. Free radical biology & medicine, 43 ((9)): (1322-1327). [PMID:17893045] |
9. Takamitsu Miyafusa,Yoshikazu Tanaka,Makoto Kuroda,Toshiko Ohta,Kouhei Tsumoto. (2008-06-10) Expression, purification, crystallization and preliminary diffraction analysis of CapF, a capsular polysaccharide-synthesis enzyme from Staphylococcus aureus.. Acta crystallographica. Section F, Structural biology and crystallization communications, 64 ((Pt 6)): (512-515). [PMID:18540063] |
10. Xiaohua Liu,Laura A Smith,Jiang Hu,Peter X Ma. (2009-01-21) Biomimetic nanofibrous gelatin/apatite composite scaffolds for bone tissue engineering.. Biomaterials, 30 ((12)): (2252-2258). [PMID:19152974] |
11. Dong Long,Daiwen Yang. (2009-02-17) Buffer interference with protein dynamics: a case study on human liver fatty acid binding protein.. Biophysical journal, 96 ((4)): (1482-1488). [PMID:19217864] |
12. Theresa E Bankston,Laura Dattolo,Giorgio Carta. (2010-03-03) pH Transients in hydroxyapatite chromatography columns-experimental evidence and phenomenological modeling.. Journal of chromatography. A, 1217 ((14)): (2123-2131). [PMID:20193952] |
13. K Nakajo,N Takahashi,D Beighton. (2010-09-04) Resistance to acidic environments of caries-associated bacteria: Bifidobacterium dentium and Bifidobacterium longum.. Caries research, 44 ((5)): (431-437). [PMID:20814202] |
14. Menglu Shi,Wei Su,Hiroshi Matsui. (2010-09-14) PbSe nanocrystal growth as nanocubes and nanorods on peptide nanotubes via different directed-assembly pathways.. Nanoscale, 2 ((11)): (2373-2376). [PMID:20835484] |
15. Yue Yuan,Tong-Jian Shen,Priyamvada Gupta,Nancy T Ho,Virgil Simplaceanu,Tsuey Chyi S Tam,Michael Hofreiter,Alan Cooper,Kevin L Campbell,Chien Ho. (2011-08-03) A biochemical--biophysical study of hemoglobins from woolly mammoth, Asian elephant, and humans.. Biochemistry, 50 ((34)): (7350-7360). [PMID:21806075] |
16. Corinne Appia-Ayme,Elaine Patrick,Matthew J Sullivan,Mark J Alston,Sarah J Field,Manal AbuOun,Muna F Anjum,Gary Rowley. (2011-09-03) Novel inducers of the envelope stress response BaeSR in Salmonella Typhimurium: BaeR is critically required for tungstate waste disposal.. PloS one, 6 ((8)): (e23713-e23713). [PMID:21886814] |
17. Shu-Chih Hsieh,Cheng-Ming Tang,Wen-Tao Huang,Ling-Ling Hsieh,Chun-Mei Lu,Chen-Jung Chang,Shan-hui Hsu. (2011-09-29) Comparison between two different methods of immobilizing NGF in poly(DL-lactic acid-co-glycolic acid) conduit for peripheral nerve regeneration by EDC/NHS/MES and genipin.. Journal of biomedical materials research. Part A, 99 ((4)): (576-585). [PMID:21953828] |
18. Kaifeng Hu,James J Ellinger,Roger A Chylla,John L Markley. (2011-10-28) Measurement of absolute concentrations of individual compounds in metabolite mixtures by gradient-selective time-zero 1H-13C HSQC with two concentration references and fast maximum likelihood reconstruction analysis.. Analytical chemistry, 83 ((24)): (9352-9360). [PMID:22029275] |
19. Špela Zupančič,Petra Kocbek,M Gulrez Zariwala,Derek Renshaw,Mine Orlu Gul,Zeeneh Elsaid,Kevin M G Taylor,Satyanarayana Somavarapu. (2014-05-24) Design and development of novel mitochondrial targeted nanocarriers, DQAsomes for curcumin inhalation.. Molecular pharmaceutics, 11 ((7)): (2334-2345). [PMID:24852198] |
20. Yi-Jun Wang,Rishil J Kathawala,Yun-Kai Zhang,Atish Patel,Priyank Kumar,Suneet Shukla,King Leung Fung,Suresh V Ambudkar,Tanaji T Talele,Zhe-Sheng Chen. (2014-06-18) Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1.. Biochemical pharmacology, 90 ((4)): (367-378). [PMID:24937702] |
21. Tongtong Ma,Lianyan Wang,Tingyuan Yang,Guanghui Ma,Siling Wang. (2014-07-02) M-cell targeted polymeric lipid nanoparticles containing a Toll-like receptor agonist to boost oral immunity.. International journal of pharmaceutics, 473 ((1-2)): (296-303). [PMID:24984067] |
22. Patricia Lopez-Sanchez,Erich Schuster,Dongjie Wang,Michael J Gidley,Anna Strom. (2015-04-23) Diffusion of macromolecules in self-assembled cellulose/hemicellulose hydrogels.. Soft matter, 11 ((20)): (4002-4010). [PMID:25898947] |
23. Tao Zhang,Ping Ren,Vishnu Chaturvedi,Sudha Chaturvedi. (2015-06-09) Development of an Agrobacterium-mediated transformation system for the cold-adapted fungi Pseudogymnoascus destructans and P. pannorum.. Fungal genetics and biology : FG & B, 81 (73-81). [PMID:26051491] |
24. S M Kelleher,R I Nooney,S P Flynn,E Clancy,M Burke,S Daly,T J Smith,S Daniels,C McDonagh. (2015-08-22) Multivalent linkers for improved covalent binding of oligonucleotides to dye-doped silica nanoparticles.. Nanotechnology, 26 ((36)): (365703-365703). [PMID:26294441] |
25. Seyed-Fakhreddin Torabi,Yi Lu. (2015-11-19) Identification of the Same Na(+)-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions.. Journal of molecular evolution, 81 ((5-6)): (225-234). [PMID:26577294] |
26. Irene Kyrmizi,Helena Ferreira,Agostinho Carvalho,Julio Alberto Landero Figueroa,Pavlos Zarmpas,Cristina Cunha,Tonia Akoumianaki,Kostas Stylianou,George S Deepe,George Samonis,João F Lacerda,António Campos,Dimitrios P Kontoyiannis,Nikolaos Mihalopoulos,Kyung J Kwon-Chung,Jamel El-Benna,Isabel Valsecchi,Anne Beauvais,Axel A Brakhage,Nuno M Neves,Jean-Paul Latge,Georgios Chamilos. (2018-06-01) Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis.. Nature microbiology, 3 ((7)): (791-803). [PMID:29849062] |
27. Kay Lockyer,Fang Gao,Robert J Francis,David Eastwood,Bhagwati Khatri,Richard Stebbings,Jeremy P Derrick,Barbara Bolgiano. (2020-02-25) Higher mass meningococcal group C-tetanus toxoid vaccines conjugated with carbodiimide correlate with greater immunogenicity.. Vaccine, 38 ((13)): (2859-2869). [PMID:32089463] |