Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M129878-50mg | 50mg | In stock | $90.90 | |
M129878-250mg | 250mg | In stock | $406.90 | |
M129878-1g | 1g | In stock | $1,462.90 | |
M129878-5g | 5g | In stock | $6,579.90 |
Synonyms | mestranol|72-33-3|Menophase|Norquen|Devocin|Ovastol|EE3ME|Ethynylestradiol 3-methyl ether|Mestranolum|3-Methoxyethynylestradiol|EE(sub3)ME|Ethynylestradiol methyl ether|3-Methylethynylestradiol|3-O-Methylethynylestradiol|Compound 33355|Inostral|3-Methylet |
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Specifications & Purity | Moligand™, ≥99% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Estrogen receptor alpha agonist |
Product Description | Pharmacological estrogen molecule1,2,3 |
ALogP | 4 |
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IUPAC Name | (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol |
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INCHI | InChI=1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,20+,21+/m1/s1 |
InChi Key | IMSSROKUHAOUJS-MJCUULBUSA-N |
Canonical SMILES | CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OC |
Isomeric SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)OC |
WGK Germany | 3 |
RTECS | RC8960000 |
PubChem CID | 6291 |
Molecular Weight | 310.43 |
Beilstein | 2625905 |
DrugBank Ligand | DB01357 |
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PubChem CID | 6291 |
CAS Registry No. | 72-33-3 |
ChEMBL Ligand | CHEMBL1201151 |
Wikipedia | Mestranol |
ChEBI | CHEBI:6784 |
PEP | mestranol |
DrugCentral Ligand | 1714 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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I2220502 | Certificate of Analysis | Jul 12, 2024 | M129878 |
I2220503 | Certificate of Analysis | Jul 12, 2024 | M129878 |
I2220504 | Certificate of Analysis | Jul 12, 2024 | M129878 |
I2220538 | Certificate of Analysis | Jul 12, 2024 | M129878 |
Solubility | DMSO 15 mg/mL Water <1 mg/mL Ethanol 25 mg/mL |
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Specific Rotation[α] | [α]D:4° (C=2,Dioxane) |
Melt Point(°C) | 151 °C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H351:Suspected of causing cancer H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H360:May damage fertility or the unborn child H362:May cause harm to breast-fed children |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 3 |
RTECS | RC8960000 |
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2. Thomas A Temes,Henrik Andersen,Daniel Gilberg,Matthias Bonerz. (2002-07-26) Determination of estrogens in sludge and sediments by liquid extraction and GC/MS/MS.. Analytical chemistry, 74 ((14)): (3498-3504). [PMID:12139060] |
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6. Hideki Mizunuma. (2004-03-24) [Treatment of osteoporosis with estrogen].. Nihon rinsho. Japanese journal of clinical medicine, 62 Suppl 2 (397-403). [PMID:15035159] |
7. Stefanie Weber,Prisca Leuschner,Peter Kämpfer,Wolfgang Dott,Juliane Hollender. (2004-08-04) Degradation of estradiol and ethinyl estradiol by activated sludge and by a defined mixed culture.. Applied microbiology and biotechnology, 67 ((1)): (106-112). [PMID:15290133] |
8. Guillermo Marconi,Martín Vilela,Ramiro Quintana,Marco Diradourián,Edgardo Young,Carlos Sueldo. (2004-12-14) New observations on endometrial physiology after transcervical injection of methylene blue dye.. Fertility and sterility, 82 ((6)): (1700-1704). [PMID:15589887] |
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11. Laura Canesi,Lucia Cecilia Lorusso,Caterina Ciacci,Michele Betti,Marco Rocchi,Giulio Pojana,Antonio Marcomini. (2006-11-28) Immunomodulation of Mytilus hemocytes by individual estrogenic chemicals and environmentally relevant mixtures of estrogens: in vitro and in vivo studies.. Aquatic toxicology (Amsterdam, Netherlands), 81 ((1)): (36-44). [PMID:17126923] |
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13. Hongqi Li,Yanxi Song,Xianfu Peng. (2008-02-08) Improved synthesis of mestranol and ethinyl estradiol (EE) related degradation products as authentic references.. Steroids, 73 ((5)): (488-494). [PMID:18255111] |
14. Denis Fourches,Julie C Barnes,Nicola C Day,Paul Bradley,Jane Z Reed,Alexander Tropsha. (2009-12-18) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.. Chemical research in toxicology, 23 ((1)): (171-183). [PMID:20014752] |
15. Asier Vallejo,Aresatz Usobiaga,Irantzu Martinez-Arkarazo,Ailette Prieto,Nestor Etxebarria,Olatz Zuloaga,Luis A Fernández. (2009-12-22) Ultrasonic-assisted derivatization of estrogenic compounds in a cup horn booster and determination by GC-MS.. Journal of separation science, 33 ((1)): (104-111). [PMID:20024927] |
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17. Ji-Hong Hu,Li Wang,Wan-Shu Li,Da-Peng Dai,Jian-Ping Cai,Guo-Xin Hu. (2015-05-01) Effect of CYP2C9 Genetic Polymorphism in a Chinese Population on the Metabolism of Mestranol in vitro.. Pharmacology, 95 ((5-6)): (218-223). [PMID:25924705] |
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20. Jun Mizutani,Muneyoshi Fukuoka,Shunji Tsubouchi,Takanobu Otsuka,Yuji Tono,Shigeki Shimizu,Nobuo Matsui. (2002-08-27) A rare case of lumbosacral meningioma: nondural attachment and possible enlargement by orally administered sex steroid.. Spine, 27 ((16)): (E377-E381). [PMID:12195080] |
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22. Tom Kouki,Miho Okamoto,Shizuko Wada,Miki Kishitake,Korehito Yamanouchi. (2004-12-21) Suppressive effect of neonatal treatment with a phytoestrogen, coumestrol, on lordosis and estrous cycle in female rats.. Brain research bulletin, 64 ((5)): (449-454). [PMID:15607833] |
23. Tsuneo Takenaka,Yoshihiko Kanno,Hiromichi Suzuki. (2005-01-13) Judicious usage of estrogen/progesterone for angiodysplasia.. Artificial organs, 29 ((1)): (88-89). [PMID:15644090] |
24. Muhammad Iqbal Choudhary,Syed Ghulam Musharraf,Zafar Ali Siddiqui,Naik Tameen Khan,Rahat Azhar Ali,Atta Ur-Rahman. (2005-08-05) Microbial transformation of mestranol by Cunninghamella elegans.. Chemical & pharmaceutical bulletin, 53 ((8)): (1011-1013). [PMID:16079537] |
25. Jari Sinkkonen,Jaana Liimatainen,Maarit Karonen,Kirsti Wiinamäki,Patrik Eklund,Rainer Sjöholm,Kalevi Pihlaja. (2007-04-25) A sesquineolignan with a spirodienone structure from Pinus sylvestris L.. Angewandte Chemie (International ed. in English), 46 ((22)): (4148-4150). [PMID:17455178] |
26. Satoshi Kawamura,Akio Sakai,Tomomichi Endo,Masaki Maruta. (2008-07-01) Atypical depression as a premonitory symptom of migraine managed by an oral contraceptive.. Psychiatry and clinical neurosciences, 62 ((3)): (365-365). [PMID:18588602] |
27. Jules Schwartz,Thomas Hunt,William B Smith,Peggy Wong,Patrick Larson,Tami Crumley,Anish Mehta,Keith Gottesdiener,Nancy Agrawal. (2009-05-16) The effect of etoricoxib on the pharmacokinetics of oral contraceptives in healthy participants.. Journal of clinical pharmacology, 49 ((7)): (807-815). [PMID:19443681] |
28. Dóra Kovács,Zalán Kádár,Gergő Mótyán,Gyula Schneider,János Wölfling,István Zupkó,Eva Frank. (2012-05-23) Synthesis, characterization and biological evaluation of some novel 17-isoxazoles in the estrone series.. Steroids, 77 ((11)): (1075-1085). [PMID:22613036] |
29. Zhichao Liu,Qiang Shi,Don Ding,Reagan Kelly,Hong Fang,Weida Tong. (2011-12-24) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).. PLoS computational biology, 7 ((12)): (e1002310-e1002310). [PMID:22194678] |