Click Here for 5% Off Your First Aladdin Purchase!
Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

Mesulergine hydrochloride , CAS No.64795-35-3, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Antagonist of 5-HT 7 receptor

  • Moligand™
Item Number
M338134
Grouped product items
SKUSizeAvailabilityPrice Qty
M338134-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$190.90
M338134-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$783.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

a D2-like dopamine receptor partial agonist

View related series
5-HT2A receptor Antagonist 5-HT2B receptor Antagonist 5-HT2C receptor Antagonist 5-HT6 receptor Antagonist 5-HT7 receptor Antagonist

Basic Description

SynonymsMesulergine|Mesulerginum|64795-35-3|Mesulergine [INN]|Mesulergina|N'-(1,6-Dimethylergolin-8alpha-yl)-N,N-dimethylsulfamide|SML95FK06I|CHEMBL12314|DTXSID3046324|CHEBI:73378|NCGC00163168-01|(6aR,9S,10aR)-9-(dimethylsulfamoylamino)-4,7-dimethyl-6,6a,8,9,10,1
Storage TempRoom temperature,Desiccated
Shipped InNormal
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Antagonist of 5-HT 7 receptor
Product Description

Mesulergine hydrochloride is a D|2|-like dopamine receptor partial agonist and a SR-2A/SR-2C antagonist.

Product Properties

Ki DataD2-like dopamine receptor: Ki= 8 nM (human)

Associated Targets

HTR2A Tclin 5-hydroxytryptamine receptor 2A 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR7 Tclin 5-hydroxytryptamine receptor 7 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C 7 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 4 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (6aR,9S,10aR)-9-(dimethylsulfamoylamino)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline
INCHI InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1
InChi Key JLVHTNZNKOSCNB-YSVLISHTSA-N
Canonical SMILES CN1CC(CC2C1CC3=CN(C4=CC=CC2=C34)C)NS(=O)(=O)N(C)C
Isomeric SMILES CN1C[C@H](C[C@H]2[C@H]1CC3=CN(C4=CC=CC2=C34)C)NS(=O)(=O)N(C)C
RTECS WO6565500
PubChem CID 68848
Molecular Weight 398.95

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySoluble in DMSO (100 mM), and water (5 mM).
Refractive Indexn20D1.68 (Predicted)

Safety and Hazards(GHS)

RTECS WO6565500

Related Documents

 SDS

 Specification Sheet

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.