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Methenamine Hippurate - 95%, high purity , DNA inhibitor, CAS No.5714-73-8, DNA inhibitor
Basic Description Synonyms Viapta | Methenamine hippurate | D00855 | 2-benzamidoacetic acid;1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane | FT-0671059 | Hexamethylenetetramine monohippurate;Hexamethylenetetramine monohippurate | 1,3,5,7-TETRAAZATRICYCLO[3.3.1.1(3),?]DECANE; 2-(PHENYLFO Specifications & Purity ≥95% Biochemical and Physiological Mechanisms Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that is hydrolyzed to formaldehyde in acid urine.Methenamine Hippurate is the component of Hiprex drug which has antibacterial activity. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type INHIBITOR Mechanism of action DNA inhibitor Product Description Information:
Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that is hydrolyzed to formaldehyde in acid urine.Methenamine Hippurate is the component of Hiprex drug which has antibacterial activity.
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2-benzamidoacetic acid;1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane INCHI InChI=1S/C9H9NO3.C6H12N4/c11-8(12)6-10-9(13)7-4-2-1-3-5-7;1-7-2-9-4-8(1)5-10(3-7)6-9/h1-5H,6H2,(H,10,13)(H,11,12);1-6H2 InChi Key ROAIXOJGRFKICW-UHFFFAOYSA-N Canonical SMILES C1N2CN3CN1CN(C2)C3.C1=CC=C(C=C1)C(=O)NCC(=O)O Isomeric SMILES C1N2CN3CN1CN(C2)C3.C1=CC=C(C=C1)C(=O)NCC(=O)O PubChem CID 21945 Molecular Weight 319.36
Chemical and Physical Properties Solubility Solubility (25°C) In vitro DMSO: 64 mg/mL (200.4 mM); Water: 64 mg/mL (200.4 mM); Ethanol: 64 mg/mL (200.4 mM); Melt Point(°C) >89°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H317: May cause an allergic skin reaction
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
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