Click Here for 5% Off Your First Aladdin Purchase!

Methicillin sodium salt - ≥95% (HPLC), high purity , CAS No.132-92-3

  • ≥95%(HPLC)
Item Number
M463724
Grouped product items
SKUSizeAvailabilityPrice Qty
M463724-50mg
50mg
In stock
$79.90

Basic Description

SynonymsMETHICILLIN SODIUM|Methicillin sodium salt|Sodium methicillin|Meticillin sodium|Belfacillin|Synticillin|Penaureus|Staficyn|Dimocillin sodium|132-92-3|Celpilline|Cinopenil|Estafcilina|Flabelline|Lucopenin|Celbenin|Penysol|Meticillin sodium salt|Methicillin
Specifications & Purity≥95% (HPLC)
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Description

Methicillin is used to study bacterium susceptibility , methicillin-resistance in Staphylococcus aureus , and to inhibit cell-wall synthesis .

Names and Identifiers

IUPAC Name sodium;(2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
INCHI InChI=1S/C17H20N2O6S.Na/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4;/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23);/q;+1/p-1/t11-,12+,15-;/m1./s1
InChi Key MGFZNWDWOKASQZ-UMLIZJHQSA-M
Canonical SMILES CC1(C(N2C(S1)C(C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)[O-])C.[Na+]
Isomeric SMILES CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)[O-])C.[Na+]
PubChem CID 23667627
Molecular Weight 402.4

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

1 results found

Lot NumberCertificate TypeDateItem
H2303874Certificate of AnalysisJul 28, 2023 M463724

Chemical and Physical Properties

SolubilitySlightly soluble in acetone. Soluble in ethanol or water
SensitivityHeat & Light & Moisture sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H317:May cause an allergic skin reaction

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

Related Documents

References

1. F G Rodgers,A O Tzianabos,T S Elliott.  (1990-01-01)  The effect of antibiotics that inhibit cell-wall, protein, and DNA synthesis on the growth and morphology of Legionella pneumophila..  Journal of medical microbiology,  31  ((1)): (37-44).  [PMID:2296040]
2. David A Bemis,Rebekah D Jones,Ricardo Videla,Stephen A Kania.  (2012-07-13)  Evaluation of cefoxitin disk diffusion breakpoint for detection of methicillin resistance in Staphylococcus pseudintermedius isolates from dogs..  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,  24  ((5)): (964-967).  [PMID:22786971]
3. Alex J McCarthy,Jodi A Lindsay,Anette Loeffler.  (2012-07-25)  Are all meticillin-resistant Staphylococcus aureus (MRSA) equal in all hosts? Epidemiological and genetic comparison between animal and human MRSA..  Veterinary dermatology,  23  ((4)): (267-275).  [PMID:22823579]
4. Ann L Bull,Leon J Worth,Michael J Richards.  (2012-07-25)  Impact of vancomycin surgical antibiotic prophylaxis on the development of methicillin-sensitive staphylococcus aureus surgical site infections: report from Australian Surveillance Data (VICNISS)..  Annals of surgery,  256  ((6)): (1089-1092).  [PMID:22824854]
5. Cheikh Fall,Abdoulaye Seck,Vincent Richard,Moustapha Ndour,Mbacke Sembene,Frederic Laurent,Sebastien Breurec.  (2012-09-08)  Epidemiology of Staphylococcus aureus in pigs and farmers in the largest farm in Dakar, Senegal..  Foodborne pathogens and disease,  ((10)): (962-965).  [PMID:22953738]
6. Madeline J Stone,John Wain,Alasdair Ivens,Theresa Feltwell,Angela M Kearns,Kathleen B Bamford.  (2012-09-25)  Harnessing the genome: development of a hierarchical typing scheme for meticillin-resistant Staphylococcus aureus..  Journal of medical microbiology,  62  ((Pt 1)): (36-45).  [PMID:23002072]
7. Susan Boyle-Vavra,Shouhui Yin,Dae Sun Jo,Christopher P Montgomery,Robert S Daum.  (2012-10-17)  VraT/YvqF is required for methicillin resistance and activation of the VraSR regulon in Staphylococcus aureus..  Antimicrobial agents and chemotherapy,  57  ((1)): (83-95).  [PMID:23070169]
8. Wenming Zhu,Nancye Clark,Jean B Patel.  (2012-10-24)  pSK41-like plasmid is necessary for Inc18-like vanA plasmid transfer from Enterococcus faecalis to Staphylococcus aureus in vitro..  Antimicrobial agents and chemotherapy,  57  ((1)): (212-219).  [PMID:23089754]
9. Erwin Verkade,Anneke M C Bergmans,Andries E Budding,Alex van Belkum,Paul Savelkoul,Anton G Buiting,Jan Kluytmans.  (2012-10-25)  Recent emergence of Staphylococcus aureus clonal complex 398 in human blood cultures..  PloS one,  ((10)): (e41855-e41855).  [PMID:23094014]
10. Rebecca Kessler.  (2012-11-03)  Superbug hideout: finding MRSA in U.S.wastewater treatment plants..  Environmental health perspectives,  120  ((11)): (A437-A437).  [PMID:23117334]
11. Briony J Hazelton,Lee C Thomas,Tuba Unver,Jonathan R Iredell.  (2012-11-10)  Rapid identification of Gram-positive pathogens and their resistance genes from positive blood culture broth using a multiplex tandem RT-PCR assay..  Journal of medical microbiology,  62  ((Pt 2)): (223-231).  [PMID:23139396]
12. Keli Cristine Reiter,Bárbara Villa,Thiago Galvão da Silva Paim,Caio Fernando de Oliveira', "Pedro Alves d'Azevedo".  (2012-11-20)  Inhibition of biofilm maturation by linezolid in meticillin-resistant Staphylococcus epidermidis clinical isolates: comparison with other drugs..  Journal of medical microbiology,  62  ((Pt 3)): (394-399).  [PMID:23161766]
13. Wei Zhu,Yonghui Zhang,William Sinko,Mary E Hensler,Joshua Olson,Katie J Molohon,Steffen Lindert,Rong Cao,Kai Li,Ke Wang,Yang Wang,Yi-Liang Liu,Anna Sankovsky,César Augusto F de Oliveira,Douglas A Mitchell,Victor Nizet,J Andrew McCammon,Eric Oldfield.  (2012-12-19)  Antibacterial drug leads targeting isoprenoid biosynthesis..  Proceedings of the National Academy of Sciences of the United States of America,  110  ((1)): (123-128).  [PMID:23248302]
14. Yong Pil Chong,Eun Sil Kim,Su-Jin Park,Ki-Ho Park,Tark Kim,Mi-Na Kim,Sung-Han Kim,Sang-Oh Lee,Sang-Ho Choi,Jun Hee Woo,Jin-Yong Jeong,Yang Soo Kim.  (2012-12-21)  Accessory gene regulator (agr) dysfunction in Staphylococcus aureus bloodstream isolates from South Korean patients..  Antimicrobial agents and chemotherapy,  57  ((3)): (1509-1512).  [PMID:23254438]
15. Kathleen Gutierrez,Meira S Halpern,Clea Sarnquist,Shila Soni,Anna Chen Arroyo,Yvonne Maldonado.  (2012-12-25)  Staphylococcal infections in children, California, USA, 1985-2009..  Emerging infectious diseases,  19  ((1)): (10-20).  [PMID:23260060]
16. Øyvind Omland,Leif Hoffmann.  (2013-01-15)  Occupational acquisition of methicillin-resistant Staphylococcus aureus in humans--a description of MRSA carrier and infected cases from the Region of North Jutland in Denmark..  Annals of agricultural and environmental medicine : AAEM,  19  ((4)): (637-640).  [PMID:23311780]
17. Yoshitsugu Iinuma,Masami Matsumura,Hisashi Baba,Hirofumi Aoki.  (2013-01-25)  [Report from the 13th Hokuriku Chapter Open Conference for the fellow of the Japanese Society of Internal Medicine: a case of 70-year-old woman who complained of fever and lumbago]..  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,  101  ((11)): (3261-3267).  [PMID:23342602]
18. Guoxiang Chao,Xiaoping Zhang,Xiaorong Zhang,Yao Huang,Lan Xu,Liping Zhou,Weixia Yang,Yuan Jiang,Feng Xue,Yantao Wu.  (2013-02-15)  Phenotypic and genotypic characterization of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA) from different sources in China..  Foodborne pathogens and disease,  10  ((3)): (214-221).  [PMID:23405883]
19. Nachum Kaplan,Donald Awrey,Elias Bardouniotis,Judd Berman,Jeremy Yethon,Henry W Pauls,Barry Hafkin.  (2013-02-26)  In vitro activity (MICs and rate of kill) of AFN-1252, a novel FabI inhibitor, in the presence of serum and in combination with other antibiotics..  Journal of chemotherapy (Florence, Italy),  25  ((1)): (18-25).  [PMID:23433440]
20. Banani Poddar,Jyoti Narayan Sahoo,Mohan Gurjar,Ratender Singh,Afzal Azim.  (2013-03-15)  Deep-vein thrombosis and septic pulmonary emboli in methicillin-sensitive Staphylococcus aureus infection..  Paediatrics and international child health,  33  ((1)): (49-52).  [PMID:23485497]
21. So-Hyun Park,Soo-Young Kim,Jung-Hyun Lee,Chulmin Park,Dong-Gun Lee.  (2013-05-28)  Community-genotype strains of methicillin-resistant Staphylococcus aureus with high-level mupirocin resistance in a neonatal intensive care unit..  Early human development,  89  ((9)): (661-665).  [PMID:23707691]
22. Jessica D Podoll,Yongxiang Liu,Le Chang,Shane Walls,Wei Wang,Xiang Wang.  (2013-09-11)  Bio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics..  Proceedings of the National Academy of Sciences of the United States of America,  110  ((39)): (15573-15578).  [PMID:24019472]
23. Paweł Kwiatkowski,Łukasz Łopusiewicz,Agata Pruss,Mateusz Kostek,Monika Sienkiewicz,Radosław Bonikowski,Iwona Wojciechowska-Koszko,Barbara Dołęgowska.  (2020-10-01)  Antibacterial Activity of Selected Essential Oil Compounds Alone and in Combination with β-Lactam Antibiotics Against MRSA Strains..  International journal of molecular sciences,  21  ((19)):   [PMID:32993130]
24. G L French,J L Ling,Y W Hui,H K Oo.  (1987-10-01)  Determination of methicillin-resistance in Staphylococcus aureus by agar dilution and disc diffusion methods..  The Journal of antimicrobial chemotherapy,  20  ((4)): (599-608).  [PMID:3680092]
25. Hong DU,Ping Zhang,Hai-ying Shen,Min Wang,Xiao-li Dai.  (2012-07-18)  [Expression, purification and application of EsxB protein in Staphylococcus aureus]..  Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine],  46  ((4)): (364-366).  [PMID:22800639]
26. Yan Q Xiong,Wessam Abdel Hady,Arnold S Bayer,Liang Chen,Barry N Kreiswirth,Soo-Jin Yang.  (2012-08-15)  Telavancin in therapy of experimental aortic valve endocarditis in rabbits due to daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus..  Antimicrobial agents and chemotherapy,  56  ((11)): (5528-5533).  [PMID:22890759]
27. Vincenzo Catena,Marco Baiocchi,Paolo Lentini,Luigi Badolati,Monica Baccarin,Daniele D Del Monte,Alessandro Rubini.  (2012-09-21)  Necrotizing pneumonia caused by Panton-Valentine leukocidin-producing methicillin-susceptible Staphylococcus aureus (MSSA)..  Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive,  20  ((3)): (205-210).  [PMID:22992562]
28. Selma Uzunović-Kamberović,Michelle I A Rijnders,Ellen E Stobberingh,Amir Ibrahimagić,Farah Kamberović,Tatjana Ille.  (2012-10-12)  Molecular characterisation of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in inpatients and outpatients in Bosnia and Herzegovina..  Wiener medizinische Wochenschrift (1946),  163  ((1-2)): (13-20).  [PMID:23053564]
29. Sebhat Erqou,Nitin Kamat,Stergios Moschos,Annie Im,Sheldon Bastacky.  (2012-10-31)  A 61 year diabetic man with methicillin-sensitive Staphylococcus aureus septic arthritis and acute renal failure: a case of IgA-dominant postinfectious glomerulonephritis..  Nephrology (Carlton, Vic.),  17  ((8)): (780-781).  [PMID:23107126]
30. Rachel E Rosenberg Goldstein,Shirley A Micallef,Shawn G Gibbs,Johnnie A Davis,Xin He,Ashish George,Lara M Kleinfelter,Nicole A Schreiber,Sampa Mukherjee,Amir Sapkota,Sam W Joseph,Amy R Sapkota.  (2012-11-06)  Methicillin-resistant Staphylococcus aureus (MRSA) detected at four U.S. wastewater treatment plants..  Environmental health perspectives,  120  ((11)): (1551-1558).  [PMID:23124279]
31. Vittoria Cinquepalmi,Rosa Monno,Luciana Fumarola,Gianpiero Ventrella,Carla Calia,Maria Fiorella Greco,Danila de Vito,Leonardo Soleo.  (2012-12-25)  Environmental contamination by dog’s faeces: a public health problem?.  International journal of environmental research and public health,  10  ((1)): (72-84).  [PMID:23263659]
32. Ulla Ruffing,Ruslan Akulenko,Markus Bischoff,Volkhard Helms,Mathias Herrmann,Lutz von Müller.  (2013-01-04)  Matched-cohort DNA microarray diversity analysis of methicillin sensitive and methicillin resistant Staphylococcus aureus isolates from hospital admission patients..  PloS one,  ((12)): (e52487-e52487).  [PMID:23285062]
33. Mia D Champion,Vanessa Gray,Carl Eberhard,Sudhir Kumar.  (2013-02-21)  The evolutionary history of amino acid variations mediating increased resistance of S. aureus identifies reversion mutations in metabolic regulators..  PloS one,  ((2)): (e56466-e56466).  [PMID:23424663]
34. Xiu-Jun Fu,Yong Fang,Min Yao.  (2013-04-05)  Antimicrobial photodynamic therapy for methicillin-resistant Staphylococcus aureus infection..  BioMed research international,  2013  (159157-159157).  [PMID:23555074]
35. Jing-Zhen Deng.  (2013-05-30)  Methicillin/per-6-(4-methoxylbenzyl)-amino-6-deoxy-β-cyclodextrin 1:1 complex and its potentiation in vitro against methicillin-resistant Staphylococcus aureus..  The Journal of antibiotics,  66  ((9)): (517-521).  [PMID:23715036]
36. Rachel E Reem,Joany Van Balen,Armando E Hoet,Colleen M Cebulla.  (2014-01-15)  Screening and characterization of Staphylococcus aureus from ophthalmology clinic surfaces: a proposed surveillance tool..  American journal of ophthalmology,  157  ((4)): (781-787).  [PMID:24412125]
37. Tetsuya Horino,Fumiya Sato,Yumiko Hosaka,Tokio Hoshina,Kumi Tamura,Kazuhiko Nakaharai,Tetsuro Kato,Yasushi Nakazawa,Masaki Yoshida,Seiji Hori.  (2014-09-25)  Predictive factors for metastatic infection in patients with bacteremia caused by methicillin-sensitive Staphylococcus aureus..  The American journal of the medical sciences,  349  ((1)): (24-28).  [PMID:25250988]
38. Benjamin M Geilich,Ilia Gelfat,Srinivas Sridhar,Anne L van de Ven,Thomas J Webster.  (2016-12-25)  Superparamagnetic iron oxide-encapsulating polymersome nanocarriers for biofilm eradication..  Biomaterials,  119  (78-85).  [PMID:28011336]

Solution Calculators