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Methyl 2，5-Dihydroxycinnamate - 95%, high purity , CAS No.63177-57-1

≥95%

CAS#: 63177-57-1
Formula: C₁₀H₁₀O₄
Molecular Weight: 194.18
MDL number: MFCD00132932
PubChem CID: 5353609

Item Number

M136980

Grouped product items
SKU	Size	Availability	Price
M136980-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$59.90
M136980-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$92.90
M136980-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$207.90
M136980-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$536.90

EGFR-kinase inhibitor

View related series

Phenylpropanoids Receptor tyrosine kinase (RTK) inhibitors

Basic Description

Synonyms	Methyl 2,5-dihydroxycinnamate\|63177-57-1\|2,5-Dihydroxycinnamic acid methyl ester\|methyl 3-(2,5-dihydroxyphenyl)acrylate\|(E)-methyl 3-(2,5-dihydroxyphenyl)acrylate\|123064-80-2\|methyl (E)-3-(2,5-dihydroxyphenyl)prop-2-enoate\|CHEMBL17329\|methyl (E)-3-(2,5-di
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Erbstatin analog. Inhibitor of EGF receptor-associated tyrosine kinases.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Product Application： An inhibitor of the EGF receptor associated tyrosine kinase

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Discover Target: EHMT2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EGFR Tclin Epidermal growth factor receptor 0 Activities

Discover Target: EGFR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SIRT2 Tchem NAD-dependent protein deacetylase sirtuin-2 0 Activities

Discover Target: SIRT2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Discover Target: ALDH1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Discover Target: MAPT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	methyl (E)-3-(2,5-dihydroxyphenyl)prop-2-enoate
INCHI	InChI=1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3/b5-2+
InChi Key	BQCNSTFWSKOWMA-GORDUTHDSA-N
Canonical SMILES	COC(=O)C=CC1=C(C=CC(=C1)O)O
Isomeric SMILES	COC(=O)/C=C/C1=C(C=CC(=C1)O)O
WGK Germany	3
PubChem CID	5353609
Molecular Weight	194.18

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
G2216411	Certificate of Analysis	Apr 07, 2024	M136980
G2216412	Certificate of Analysis	Apr 07, 2024	M136980
G2216413	Certificate of Analysis	Apr 07, 2024	M136980
G2216414	Certificate of Analysis	Apr 07, 2024	M136980

Solubility

Solvent:ethanol, Max Conc. mg/mL: None, Max Conc. mM: 100

Melt Point(°C)

182 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H311:Toxic in contact with skin H331:Toxic if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3

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