methylnaltrexone , CAS No.83387-25-1, Antagonist of δ receptor;Antagonist of κ receptor;Antagonist of μ receptor

Item Number

M611834

Grouped product items
SKU	Size	Availability	Price	Qty
M611834-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,300.90
M611834-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

Basic Description

Synonyms	Methylnaltrexone\|Methylnaltrexonium\|Naltrexone MB\|N-Methylnaltrexone\|83387-25-1\|Quaternary ammonium naltrexone\|MNTX\|MRZ 2663\|Mrz-2663\|DTXSID20873339\|17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one\|Methylnaltrexone ion\|Morphinanium, 17-(c
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of δ receptor;Antagonist of κ receptor;Antagonist of μ receptor

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one
INCHI	InChI=1S/C21H25NO4/c1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13/h4-5,12,16,19,25H,2-3,6-11H2,1H3/p+1/t16-,19+,20+,21-,22?/m1/s1
InChi Key	JVLBPIPGETUEET-GAAHOAFPSA-O
Canonical SMILES	O=C1CC[C@@]2([C@@]34[C@H]1Oc1c4c(C[C@H]2[N+](CC3)(C)CC2CC2)ccc1O)O
Isomeric SMILES	C[N+]1(CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O)CC6CC6
PubChem CID	5361918