(±)-Metoprolol (+)-tartrate salt - analytical standard, high purity , Beta-1 adrenergic receptor antagonist, CAS No.56392-17-7, Beta-1 adrenergic receptor antagonist

Item Number

M111944

Grouped product items
SKU	Size	Availability	Price	Qty
M111944-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$102.90

β 1 Adrenoceptor antagonist

Basic Description

Synonyms	Metoprolol tartrate\|56392-17-7\|1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol 2,3-dihydroxysuccinate (2:1)\|Seloken\|Metoprolol (Tartrate)\|1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)-propan-2-ol 2,3-dihydroxysuccinate (2:1)\|NSC-757105\|Pres
Specifications & Purity	analytical standard
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	analytical standard
Action Type	ANTAGONIST
Mechanism of action	Beta-1 adrenergic receptor antagonist

Names and Identifiers

IUPAC Name	2,3-dihydroxybutanedioic acid;1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
INCHI	InChI=1S/2C15H25NO3.C4H6O6/c21-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h24-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)
InChi Key	YGULWPYYGQCFMP-UHFFFAOYSA-N
Canonical SMILES	CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O
Isomeric SMILES	CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O
PubChem CID	6420057
Molecular Weight	684.81

Certificates

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2 results found

Lot Number	Certificate Type	Date	Item
C1729022	Certificate of Analysis	Sep 19, 2022	M111944
J2019258	Certificate of Analysis	Aug 05, 2022	M111944

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.

References

1. Lai J et al.. (2019) ß-Adrenoceptor signaling regulates proliferation and contraction of human bladder smooth muscle cells under pathological hydrostatic pressure.. J Cell Biochem, 120 (10): (17872-17886). [PMID:31161623]
2. Giurdanella G et al.. (2021) The Anti-Inflammatory Effect of the ß1-Adrenergic Receptor Antagonist Metoprolol on High Glucose Treated Human Microvascular Retinal Endothelial Cells.. Cells, 11 [PMID:35011613]

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Basic Description