Potent, reversible 20S and 26S proteasome inhibitor (K i values are 21 and 35 nM, respectively). Inhibits chymotrypsin-like activity. Shows proapoptotic effect in vitro .
Storage Temp
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
1.Mori S, Tanaka K, Omura S, Saito Y. (1995) Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway.. J Biol Chem, 270 (49):(29447-52). [PMID:7493983][10.1021/op500134e]
2.Hirakawa T et al.. (2019) LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair.. Plant Physiol, 181 (2):(499-509). [PMID:31366719]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
F2305512