Microcrystalline Cellulose and Carboxymethylcellulose Sodium - Ph. Eur., NF, E 460 (i) & E 466, high purity

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Item Number
M498254
View related series
Cellulose

Basic Description

Specifications & PurityPh.Eur., NF, E 460(i), E 466
Shipped InNormal
GradeE 460(i), E 466, NF, Ph.Eur.
Product Description

M498254 is a synergistic, co-processed composite consisting of microcrystalline cellulose (MCC) and sodium carboxymethylcellulose (Na-CMC). It is a unique suspending and emulsifying agent, which facilitates a wide range of liquid dosage forms. Due to its extraordinary stabilizing mechanism, M498254 can be used with a broad variety of active pharmaceutical ingredients (APIs), offering the opportunity for new applications and line extensions for existing products.

M498254 is a free flowing powder. After activation, MCG builds an opaque-white dispersion which masks insoluble particles, giving the suspension a homogenous appearance. The dispersed M498254 is distinguished by an odorless and tasteless, smooth but not slimy mouth feel, and handles flavors well. Upon agitation, MCG dispersions show a time-dependent decrease in viscosity and become liquid. A complete, also time-dependent, regeneration of the viscosity takes place during a subsequent rest period. 


Benefits:

1.Easy handling of dry powder

2.Heat stability

3.Compatibility with a wide range of ingredients

4.Stable over a wide pH range

5.Safe for us in animal health products, pediatric 6.suspensions, and nutraceuti


Product specifications and parameters:

SKU

NaCMC (%)

Particle Size

Viscosity
(mPa.s)

Main Application

Pack Size

M498254-581P-500g

8.3 – 13.8

>250 µm (60 mesh):
max. 0.1%
>75 µm (200 mesh):
max. 35%

72 – 168
(1.2% solids)

For "ready-to-use" suspensions and emulsion prepared with high shear forces.

500g

M498254-591P-500g

8.3 – 13.8

>250 µm (60 mesh):
max. 0.1%
>45 µm (325 mesh):
max. 45%

39 – 91
(1.2% solids)

 

500g

M498254-611P-500g

11.3 – 18.8

>250 µm (60 mesh):
max. 0.1%
>45 µm (325 mesh):
max. 50%

50 – 118
(2.6% solids)

For reconstitutable dry suspensions.

500g

M498254-811P-500g

11.3 – 18.8

>250 µm (60 mesh):
max. 3%

2400 – 5600
(2.6% solids)

Highly effective dispersible cellulose grade for a variety of suspensions, emulsions, and spray applications.

500g


Certificates

Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
H2428229Certificate of AnalysisMay 17, 2024 M498254
H2428232Certificate of AnalysisMay 17, 2024 M498254
H2428233Certificate of AnalysisMay 17, 2024 M498254
H2428249Certificate of AnalysisMay 17, 2024 M498254
H2428250Certificate of AnalysisMay 17, 2024 M498254
H2402648Certificate of AnalysisApr 16, 2024 M498254
H2402649Certificate of AnalysisApr 16, 2024 M498254

Chemical and Physical Properties

SensitivityHeat and moisture sensitive

Related Documents

Solution Calculators