Basic Description

Synonyms

Specifications & Purity

Ph. Eur., NF, JP,ChP, E 460(i), FCC

Shipped In

Normal

Grade

ChP, E 460(i), JP, NF, Ph.Eur.

Product Description

Microcrystalline cellulose is very strong and chemically inert, so it is a very ideal carrier. API layered microcrystalline cellulose can be filled into capsules or pressed into tablets. They have a very tight particle size distribution, which can better control and improve the consistency of API release between batches. The uniformity of particle size minimizes the risk of packaging or tablet pressing, resulting in higher uniformity of API content. In addition, different APIs can be used in a variety of concentrates and combined with pellet core coating in a unit dose.

Product specifications

SKU	Average Particle Size by Laser Diffraction (µm)	Bulk Density (g/mL)	Main Application
M489093-01	15	max 0.26	Very fine grade, which gives a pleasant mouth feeling, masks bitter tastes and supports flavors.
M489093-02	65	0.26–0.31	Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.
M489093-03	65	0.26-0.34	Same quality as grade 101/50M, but very low moisture content (< 1.5 %) for processing water-sensitive actives.
M489093-04	65	0.35-0.46	Same quality as grade 101, but increased bulk density and improved flow properties.
M489093-05	130	0.28-0.33	Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.
M489093-06	130	0.30-0.36	Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives
M489093-07	130	0.35-0.50	Same quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives.
M489093-08	170/175	0.28-0.34	Coarse, DC-grade MCC.
M489093-09	180	0.30-0.36	Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives.
M489093-10	170	0.32-0.40	Same quality to grade 12, but very low moisture content (<1.5 %) for processing water-sensitive actives.
M489093-11	250	0.31-0.37	Large size MCC grade with excellent flow properties for a variety of direct compression formulations.
M489093-12	250	0.33-0.40	Same quality to grades 200/LP200, but very low moisture content (<1.5 %) for processing water-sensitive actives.
M489093-13	220	0.20-0.37	Coarse grained microcrystalline cellulose has good compressibility and adhesion, and good fluidity. Even for active ingredients with low content and fine particle size, tablets with good content uniformity and small differences in tablet weight can be obtained.

Benefits

1.High compactability,

2.Robust tablets with low friability,

3.High production yields,

4.Practically inert – compatible with most APIs,

5.Created from sustainable organic materials,

6.Contains no additives, impurities, or irradiated components,

7.Advanced carton packaging design for fast NIR identification.

Names and Identifiers

IUPAC Name	(6S)-2-(hydroxymethyl)-6-[(3S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
INCHI	InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1
InChi Key	GUBGYTABKSRVRQ-WFVLMXAXSA-N
Isomeric SMILES	C(C1[C@H](C(C(C(O1)O)O)O)O[C@H]2C(C(C(C(O2)CO)O)O)O)O
WGK Germany	3
RTECS	FJ5691460
PubChem CID	16211032

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

24 results found

Lot Number	Certificate Type	Date	Item
G2410418	Certificate of Analysis	May 08, 2024	M489093
G2410443	Certificate of Analysis	May 08, 2024	M489093
H2402646	Certificate of Analysis	Apr 10, 2024	M489093
H2402647	Certificate of Analysis	Apr 10, 2024	M489093
H2402645	Certificate of Analysis	Apr 10, 2024	M489093
H2402644	Certificate of Analysis	Apr 10, 2024	M489093
H2402643	Certificate of Analysis	Apr 10, 2024	M489093
G2424086	Certificate of Analysis	Apr 02, 2024	M489093
G2424085	Certificate of Analysis	Apr 02, 2024	M489093
G2424082	Certificate of Analysis	Apr 02, 2024	M489093
G2424083	Certificate of Analysis	Apr 02, 2024	M489093
G2424084	Certificate of Analysis	Apr 02, 2024	M489093
G2424081	Certificate of Analysis	Mar 28, 2024	M489093
G2424080	Certificate of Analysis	Mar 28, 2024	M489093
G2424079	Certificate of Analysis	Mar 28, 2024	M489093
G2424078	Certificate of Analysis	Mar 28, 2024	M489093
G2424077	Certificate of Analysis	Mar 28, 2024	M489093
A2416609	Certificate of Analysis	Sep 26, 2023	M489093
A2416611	Certificate of Analysis	Sep 26, 2023	M489093
J2320194	Certificate of Analysis	Sep 19, 2023	M489093
J2320195	Certificate of Analysis	Sep 19, 2023	M489093
J2320193	Certificate of Analysis	Sep 19, 2023	M489093
J2320196	Certificate of Analysis	Sep 19, 2023	M489093
G23131114	Certificate of Analysis	Jul 04, 2023	M489093

Safety and Hazards(GHS)

WGK Germany	3
RTECS	FJ5691460

Citations of This Product

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61. Zhiping Su, Lan Cui, Huanhuan Zhang, Lei Xiao, Bing Chi, Haiayan Xu, Liping Ning, Shanshan Jia, Xiaohui Wang. (2023) Robust, waterproof, and degradable cellulose-based polyimine vitrimer for plastic replacement. CHEMICAL ENGINEERING JOURNAL, 471 (144501). [PMID:]
62. Xingfu Zi, Hongming Wu, Jiling Song, Weidi He, Lu Xia, Jianbing Guo, Sihai Luo, Wei Yan. (2023) Electrospun Sandwich-like Structure of PVDF-HFP/Cellulose/PVDF-HFP Membrane for Lithium-Ion Batteries. MOLECULES, 28 (13): (4998). [PMID:37446661]
63. Jun Shi, Xiaoshan Zhang, Sabarinathan Ravichandran, Shirong Sun, Yulong Li, Ruoyu Wu, Wanxuan Luo, Hongmei Xing, Wenli Zhang. (2023) Locking nitrogen dopants in porous carbons through in situ grafting strategy for enhanced oxygen reduction reactions. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (35532). [PMID:]
64. Shoucun Zhang, Yujing Bian, Xueyin Yan, Guoli Fang, Shengwei Guo. (2023) Preparation of CO2 responsive cellulose composite adsorbent and its application in protein separation. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (33): (e54268). [PMID:]
65. Yuting Wu, Qilin Gui, Han Zhang, Honghong Li, Bin Li, Ming Liu, Yingquan Chen, Shihong Zhang, Haiping Yang, Hanping Chen. (2023) Effect of biomass components’ interaction on the pyrolysis reaction kinetics and small-molecule product release characteristics. JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 173 (106039). [PMID:]
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48. Jiangang Zhou, Congzhen Xie, Rui Wang, Huasong Xu, Bin Gou, Hao Yang, Licheng Li. (2023) Ultrahigh in-plane thermal conductive epoxy composites by cellulose-supported GnPs@PDA skeleton under stress-induced orientation strategy. DIAMOND AND RELATED MATERIALS, 139 (110340). [PMID:]
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51. Li-Li Sun, Yu Li, Xue-Fei Cao, Shuang-Quan Yao, Shao-Ni Sun. (2023) Insights on structure and antioxidant properties of lignin extracted from Eucalyptus by deep eutectic solvent/2-methyltetrahydrofuran biphasic system treatment. INDUSTRIAL CROPS AND PRODUCTS, 204 (117271). [PMID:]
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54. Duoduo He, Liying Qian, Xingyu Chen, Beihai He, Junrong Li. (2023) Durable cellulose paper by grafting thiol groups and controlling silver deposition for ultrahigh electromagnetic interference shielding. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 248 (125972). [PMID:37499713]
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58. Zhaoyi Li, Zhen Sun, Guan Zhang. (2023) Combining heterogeneous photocatalysis and enzymatic catalysis via membrane: Conversion of biomass for H2 production from water. APPLIED CATALYSIS B-ENVIRONMENTAL, 338 (123069). [PMID:]
59. Ran Liu, Yuanlong Guo, Min Pei, Yumei Chen, Lihua Zhang, Long Li, Qin Chen, Yaozhu Tian, Haibo Xie. (2023) Cellulose levulinate ester as a robust building block for the synthesis of fully biobased functional cellulose esters. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 246 (125654). [PMID:37399870]
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61. Zhiping Su, Lan Cui, Huanhuan Zhang, Lei Xiao, Bing Chi, Haiayan Xu, Liping Ning, Shanshan Jia, Xiaohui Wang. (2023) Robust, waterproof, and degradable cellulose-based polyimine vitrimer for plastic replacement. CHEMICAL ENGINEERING JOURNAL, 471 (144501). [PMID:]
62. Xingfu Zi, Hongming Wu, Jiling Song, Weidi He, Lu Xia, Jianbing Guo, Sihai Luo, Wei Yan. (2023) Electrospun Sandwich-like Structure of PVDF-HFP/Cellulose/PVDF-HFP Membrane for Lithium-Ion Batteries. MOLECULES, 28 (13): (4998). [PMID:37446661]
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64. Shoucun Zhang, Yujing Bian, Xueyin Yan, Guoli Fang, Shengwei Guo. (2023) Preparation of CO2 responsive cellulose composite adsorbent and its application in protein separation. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (33): (e54268). [PMID:]
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66. Srinivasan Vinju Vasudevan, Jin Cai, Junming Xu, Hongjian Lin, Hongliang Wang, Quan Bu. (2023) Microwave-Assisted Catalytic Conversion of 5-HMF for Biofuel Additives by Molybdophosphoric Acid Encapsulated KCC-1. Catalysts, 13 (6): (969). [PMID:]
67. Jing-Jing Luo, Ming-Shuai Sun, Boyuan Tang, Yan Zhou, Wen-Ting Chen, Wen-Qiang Gong, Song Han, Fei-Feng Mao, Zhang-Min Li, Duan-Jian Tao. (2023) Solvent-Controlled Product Distribution in Vanillin Hydrogenation over a N-Doped Carbon-Supported Nickel Catalyst. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 62 (23): (9134–9143). [PMID:]
68. Xiangli Gao, Huan Liu, Jianbo Shuai, Junmeng Zhao, Guowen Zhou, Quanbo Huang, Hao Ling, Wenjiao Ge, Xiaohui Wang. (2023) Rapid transesterification of cellulose in a novel DBU-derived ionic liquid: Efficient synthesis of highly substituted cellulose acetate. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 242 (125133). [PMID:37263323]
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70. Tihang Liu, Jiangang Wang, Hongyou Cui, Jinghua Wang. (2023) Conversion of biomass-derived sugars to 1,1,2-trialkoxyethane via a [2 + 4] retro-aldol reaction over alkaline and alkaline earth metal salts of phosphotungstic acid. GREEN CHEMISTRY, 25 (11): (4565-4576). [PMID:]
71. Lin Zhang, Jili Yuan, Qinqin Xu, Fazhi Zhang, Qi Sun, Haibo Xie. (2023) Noble-metal-free Co-N-C catalyst derived from cellulose-based poly(ionic liquid)s for highly efficient oxygen reduction reaction. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 242 (125110). [PMID:37257539]
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73. Miao Wang, Shuai Zhang, Xiangjun Liu, Yayun Ma, Junqi Wang. (2023) Catalytic co-pyrolysis of cellulose over alkali and alkaline earth metal salts for levoglucosan production. INDUSTRIAL CROPS AND PRODUCTS, 201 (116925). [PMID:]
74. Pu Huang, Xinzheng Wei, Xinmei Wang, Zhengjun Gu, Yafei Guo, Chuanwen Zhao. (2023) Facile fabrication of silica aerogel supported amine adsorbent pellets for Low-concentration CO2 removal from confined spaces. CHEMICAL ENGINEERING JOURNAL, 468 (143629). [PMID:]
75. Siyu Li, Weijun Shan, Ting Rao, Yanou Qi, Ying Xiong, Zhenning Lou, Haibiao Yu, Junshuo Cui, Xiaogeng Feng. (2023) Facile synthesis of a novel CAU-17/CSG composite for the trace electrochemical analysis of Zn2+, Cd2+ and Pb2+. MICROCHEMICAL JOURNAL, 191 (108861). [PMID:]
76. De-Fa Hou, Meng-Lei Li, Pei-Yao Li, Ling Zhou, Kai Zhang, Zheng-Ying Liu, Wei Yang, Ming-Bo Yang. (2023) Efficient Conversion of Cellulose to Thermoplastics by Mechanochemical Esterification. ACS Sustainable Chemistry & Engineering, 11 (20): (7655–7663). [PMID:]
77. Mengyu Dou, Yan Qiao, Xu Hu, Hengyang Miao, Ligong Zhou, Xuekuan Li, Xianglin Hou, Yingxiong Wang, Mingxing Tang. (2023) Gradient porous biochar materials with high specific surface area as supports for Pd/C catalysts for efficient maleic acid hydrogenation. Molecular Catalysis, 545 (113218). [PMID:]
78. Yinan Tang, Lu Lu, Xiaoxian Zang, Buhuan Wang, Xiangrong Ye. (2023) Tailored Properties of Carbon for Supercapacitors by Blending Lignin and Cellulose to Mimic Biomass as Carbonaceous Precursor. ChemSusChem, 16 (17): (e202300357). [PMID:37150752]
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80. Qiuyan Zhang, Jie Chen, Di Li, Ling Sun, Yuanlin Ren, Chunzu Cheng, Xiaohui Liu. (2023) Simultaneous enhancement of mechanical strength and flame retardancy of lyocell fiber via filling fire-resistant cellulose-based derivative. INDUSTRIAL CROPS AND PRODUCTS, 199 (116757). [PMID:]
81. Yong Xie, Qingqing Liu, Haibo Liu, Zhiping Fan, Jia Shi, Xiong Liu. (2023) Effect of various thermal processing on the structural and in vitro prebiotic characteristics of β-glucan from Hulless Barley. FOOD HYDROCOLLOIDS, 142 (108818). [PMID:]
82. Guozhi Fan, Yi Chen, Yuchan Lu, Qunpeng Cheng, Bo Chai, Guangsen Song. (2023) Co-production of 5-hydroxymethyl furfural and furfural from holocellulose over UiO-66-derived acid-base catalysts. CHEMICAL ENGINEERING SCIENCE, 276 (118768). [PMID:]
83. Kaifeng Lu, Yifan Wang, Lingjun Zhu, Bo Xing, Shurong Wang. (2023) Efficient Conversion of Biomass-Derived Saccharides to Levulinic Acid Using Silicotungstic Acid. ENERGY & FUELS, 37 (9): (6642–6650). [PMID:]
84. Qiang Lu, Yuefang Chen, Weipeng Song, Chaonan Tao, Junhua Zhang, Yong Sun, Lincai Peng, Huai Liu. (2023) Mechanistic role of γ-valerolactone co-solvent to promote ethyl levulinate production from cellulose transformation in ethanol. FUEL, 346 (128371). [PMID:]
85. Runni Wu, Kin Wa Kwan, Yahua Wang, Alfonso Hing Wan Ngan. (2023) Air-Working Electrochemical Actuator and Ionic Sensor Based on Manganese Dioxide/Gelatin-Glycerol Composites. Advanced Materials Technologies, 8 (13): (2202062). [PMID:]
86. Shangzhong Zhang, Yi Duan, Changchang Teng, Hongdong Quan, Xiuguo Yang, Hongyan Li, Xiaohe Li, Lifeng Yan. (2023) Fast and Selective Degradation of Biomass for Xylose, Glucose and Lignin under Mild Conditions. MOLECULES, 28 (8): (3306). [PMID:37110540]
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88. Jin Yuan, Tian Hongwu, Gao Zhen, Yang Guiyan, Dong Daming. (2023) Oil content analysis of corn seeds using a hand-held Raman spectrometer and spectral peak decomposition algorithm. Frontiers in Plant Science, 14 [PMID:37077627]
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90. Junfeng Cheng, Hualin Wang. (2023) Construction and application of nano ZnO/eugenol@yam starch/microcrystalline cellulose active antibacterial film. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 239 (124215). [PMID:36996962]
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92. Yuanlong Guo, Yang You, Gu Guo, Zixiang Chen, Wei Peng, Lijie Hu, Songmiao Liang, Haibo Xie. (2023) Facile preparation of cellulose/lignosulfonate derivatives composite films with high UV-shielding and gas barrier properties. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 237 (124218). [PMID:36990419]
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94. Yinan Li, Jun Wang, Jiajia Guo, Chenglong Fu, Liulian Huang, Lihui Chen, Yonghao Ni, Qinghong Zheng. (2023) UV and IR dual light triggered cellulose-based invisible actuators with high sensitivity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 238 (124031). [PMID:36933599]
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97. Li Zhishuncheng, Yang Can, Qu Guangfei, Cui Qingyuan, Yang Yixin, Ren Yuanchuan, Yang Yuyi, Wang Fang. (2023) Chitosan-modified magnetic carbon nanomaterials with high efficiency, controlled motility, and reusability—for removal of chromium ions from real wastewater. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (17): (51271-51287). [PMID:36809614]
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101. Jiahao Qiu, Xingzhong Guo, Wei Lei, Ronghua Ding, Yun Zhang, Hui Yang. (2023) Facile Preparation of Cellulose Aerogels with Controllable Pore Structure. Nanomaterials, 13 (3): (613). [PMID:36770574]
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106. Jiawei Li, Jie Jin, Yunao Zhao, Ziwei Zou, Yunchao Wu, Jintao Sun, Jinxia Xia. (2023) Enhancing phosphorus bioavailability in sewage sludge through co-hydrothermal treatment with biomass. Journal of Water Process Engineering, 51 (103448). [PMID:]
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109. Longfei Xie, Le Gou, Donghai Xu, Krzysztof Kapusta, Liyi Dai, Yuanyuan Wang. (2023) Coupling influences of organic components and temperature on nitrogen transformation and hydrochar characterization during hydrothermal carbonization of sewage sludge. SCIENCE OF THE TOTAL ENVIRONMENT, 866 (161354). [PMID:36603624]
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116. Bo Wang, Kai Li, Cheng-bo Zhang, Bin Hu, Yan-qin Huang, Ti-peng Wang, Qiang Lu. (2023) Influence of cellulose ultrastructure on the catalytic pyrolysis for selective production of levoglucosenone. INDUSTRIAL CROPS AND PRODUCTS, 192 (116072). [PMID:]
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123. Yang Zhang, Shiqiang Cui, He Liao, Yue Zhang, Yumei Zhang, Huaping Wang. (2023) Poly(butylene succinate)/cellulose composite monofilaments with microelastic response based on interfacial bonding. CARBOHYDRATE POLYMERS, 302 (120387). [PMID:36604065]
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Microcrystalline Cellulose - Ph. Eur., NF, JP,ChP, E 460(i), FCC, high purity , CAS No.9004-34-6