Midostaurin-d 5 is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk , Flk-1, Akt , PKA , c-Kit , c-Fgr, c-Src, FLT3 , PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM.
Biological Activity:Midostaurin-d 5 is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk , Flk-1 , Akt , PKA , c-Kit , c-Fgr, c-Src, FLT3 , PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM.