Grouped product items

SKU

Size

Availability

Price

Qty

M424931-1ml

1ml

Available within 8-12 weeks(?)

$241.90

Basic Description

Synonyms	misoprostol\|59122-46-2\|Cytotec\|Isprelor\|Misoprostolum\|Misoprost\|Misoprostil\|Misotol\|SC-29333\|Misogon\|Misotac\|Misoprostolum [INN-Latin]\|CCRIS 6859\|Misodel\|HSDB 3573\|SC 29333\|UNII-0E43V0BB57\|BRN 4155643\|DTXSID7020897\|MVI 200\|0E43V0BB57\|methyl 7-[(1R,2R,3R)-
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	PGE1 analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-a
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Cytoprotective PGE₁ analog that prevents NSAID-induced gastric ulceration. PGE₁ analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.

Product Properties

ALogP	3.7

Associated Targets

CAMTA2 Tbio Calmodulin-binding transcription activator 2 0 Activities

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CNR1 Tclin Cannabinoid receptor 1 0 Activities

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DRD1 Tclin D(1A) dopamine receptor 0 Activities

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DRD2 Tclin D(2) dopamine receptor 0 Activities

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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

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EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

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NR3C1 Tclin Glucocorticoid receptor 0 Activities

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AVPR1A Tclin Vasopressin V1a receptor 0 Activities

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HRH3 Tclin Histamine H3 receptor 0 Activities

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HRH1 Tclin Histamine H1 receptor 0 Activities

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SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

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SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

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PTGER2 Tclin Prostaglandin E2 receptor EP2 subtype 1 Activities

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PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

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PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

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PTGER4 Tclin Prostaglandin E2 receptor EP4 subtype 1 Activities

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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

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PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

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DRD3 Tclin D(3) dopamine receptor 0 Activities

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CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

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ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

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CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

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ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

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HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

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ADORA2A Tclin Adenosine receptor A2a 0 Activities

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities

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ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

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ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

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ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

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AR Tclin Androgen receptor 0 Activities

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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

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ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

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HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

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ADORA1 Tclin Adenosine receptor A1 0 Activities

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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

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ADORA3 Tchem Adenosine receptor A3 0 Activities

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HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

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TBXA2R Tclin Thromboxane A2 receptor 0 Activities

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EDNRA Tclin Endothelin-1 receptor 0 Activities

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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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OPRD1 Tclin Delta-type opioid receptor 0 Activities

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OPRK1 Tclin Kappa-type opioid receptor 0 Activities

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OPRM1 Tclin Mu-type opioid receptor 0 Activities

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MLNR Tchem Motilin receptor 0 Activities

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Names and Identifiers

IUPAC Name	methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate
INCHI	InChI=1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/m1/s1
InChi Key	OJLOPKGSLYJEMD-URPKTTJQSA-N
Canonical SMILES	CCCCC(C)(CC=CC1C(CC(=O)C1CCCCCCC(=O)OC)O)O
Isomeric SMILES	CCCCC(C)(C/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)OC)O)O
WGK Germany	3
PubChem CID	5282381
Molecular Weight	382.53

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H360:May damage fertility or the unborn child
Precautionary Statements	P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/... P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention.
WGK Germany	3

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Misoprostol - 10mM in DMSO, high purity , CAS No.59122-46-2