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Misoprostol free acid - ≥90%, high purity , CAS No.112137-89-0

  • ≥90%
Item Number
M463159
Grouped product items
SKUSizeAvailabilityPrice Qty
M463159-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$475.90

Basic Description

SynonymsMisoprostol acid|112137-89-0|66792-31-2|Misoprostol Acid (10 mg in 1 mL Methyl Acetate)|misoprostol (free acid form)|SC 30695|7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoic acid|12Z0SU967A|SC-30695|MISOPROSTOL, FRE
Specifications & Purity≥90%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets

BRD4 Tchem Bromodomain-containing protein 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CDK2 Tchem Cyclin-dependent kinase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FGFR3 Tclin Fibroblast growth factor receptor 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CSNK1D Tchem Casein kinase I isoform delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRIM24 Tchem Transcription intermediary factor 1-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER2 Tclin Prostaglandin E2 receptor EP2 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER4 Tclin Prostaglandin E2 receptor EP4 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER3 Tclin Prostaglandin E2 receptor EP3 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BRPF1 Tchem Peregrin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AURKA Tchem Aurora kinase A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GSK3B Tclin Glycogen synthase kinase-3 beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoic acid
INCHI InChI=1S/C21H36O5/c1-3-4-13-21(2,26)14-9-11-17-16(18(22)15-19(17)23)10-7-5-6-8-12-20(24)25/h9,11,16-17,19,23,26H,3-8,10,12-15H2,1-2H3,(H,24,25)/b11-9+/t16-,17-,19-,21?/m1/s1
InChi Key CNWGPXZGIIOYDL-MKYGPDKMSA-N
Canonical SMILES CCCCC(C)(CC=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
Isomeric SMILES CCCCC(C)(C/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O
PubChem CID 6436406
Molecular Weight 368.5

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H301:Toxic if swallowed

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

References

1. D Y Graham,N M Agrawal,S H Roth.  (1988-12-03)  Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial..  Lancet (London, England),  ((8623)): (1277-1280).  [PMID:2904006]
2. Marco Lazzaroni,Gabriele Bianchi Porro.  (2009-02-06)  Management of NSAID-induced gastrointestinal toxicity: focus on proton pump inhibitors..  Drugs,  69  ((1)): (51-69).  [PMID:19192936]
3. A Elati,A D Weeks.  (2009-09-26)  The use of misoprostol in obstetrics and gynaecology..  BJOG : an international journal of obstetrics and gynaecology,  116 Suppl 1  (61-69).  [PMID:19740175]
4. Wendy R Sheldon,Jennifer Blum,Jill Durocher,Beverly Winikoff.  (2012-01-12)  Misoprostol for the prevention and treatment of postpartum hemorrhage..  Expert opinion on investigational drugs,  21  ((2)): (235-250).  [PMID:22233426]
5. Bahar Javdan,Jaime G Lopez,Pranatchareeya Chankhamjon,Ying-Chiang J Lee,Raphaella Hull,Qihao Wu,Xiaojuan Wang,Seema Chatterjee,Mohamed S Donia.  (2020-06-12)  Personalized Mapping of Drug Metabolism by the Human Gut Microbiome..  Cell,  181  ((7)): (1661-1679).  [PMID:32526207]

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