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MK-0159 - 99%, high purity , CAS No.2641484-61-7

Item Number

M648927

Grouped product items
SKU	Size	Availability	Price	Qty
M648927-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$160.90
M648927-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$240.90

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Basic Description

Specifications & Purity	99%
Storage Temp	Store at 2-8°C,Protected from light,Desiccated
Shipped In	Wet ice
Product Description	MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD + (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart Form:Solid IC50& Target:IC 50 : 3 nM (mouse CD38), 22 ± 5 nM (hCD38), 70 nM (rat CD38)

Canonical SMILES	O=C(C1=C2C(NC=C2)=NC(C3=CN=CS3)=C1)N[C@H]4CC[C@H](OCCOC)CC4
Molecular Weight	400.49

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Solubility	DMSO : 100 mg/mL (249.69 mM; Need ultrasonic)

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