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MK 212 hydrochloride - ≥99%, high purity , CAS No.64022-27-1, Agonist of 5-HT 2A receptor;Agonist of 5-HT 2B receptor;Agonist of 5-HT 2C receptor

Moligand™
≥99%

CAS#: 64022-27-1
Formula: C4H9NO2
Molecular Weight: 103.12
EC Number: 262-883-0
PubChem CID: 107992

Item Number

M335875

Grouped product items
SKU	Size	Availability	Price	Qty
M335875-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$109.90
M335875-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$449.90

a SR-2C agonist

View related series

5-HT2A receptor Agonist 5-HT2B receptor Agonist 5-HT2C receptor Agonist

Basic Description

Synonyms	64022-27-1\|MK-212\|2-Chloro-6-(1-piperazinyl)pyrazine\|2-chloro-6-(piperazin-1-yl)pyrazine\|MK 212\|6-Chloro-2-(1-piperazinyl)pyrazine\|2-chloro-6-piperazin-1-ylpyrazine\|Pyrazine, 2-chloro-6-(1-piperazinyl)-\|CHEMBL269521\|62C3N7238U\|NSC-317326\|UNII-62C3N7238U\|M
Specifications & Purity	Moligand™, ≥99%
Storage Temp	Room temperature
Shipped In	Normal
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of 5-HT 2A receptor;Agonist of 5-HT 2B receptor;Agonist of 5-HT 2C receptor
Product Description	MK 212 hydrochloride is a SR-2C agonist.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

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CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

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DRD1 Tclin D(1A) dopamine receptor 0 Activities

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DRD2 Tclin D(2) dopamine receptor 0 Activities

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CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

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CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

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KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities

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RGS4 Tchem Regulator of G-protein signaling 4 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1B Tclin 5-hydroxytryptamine receptor 1B 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

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HTR2C Tclin 5-hydroxytryptamine receptor 2C 2 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Discover Target: KDM4E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-chloro-6-piperazin-1-ylpyrazine
INCHI	InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2
InChi Key	CJAWPFJGFFNXQI-UHFFFAOYSA-N
Canonical SMILES	C1CN(CCN1)C2=CN=CC(=N2)Cl
Isomeric SMILES	C1CN(CCN1)C2=CN=CC(=N2)Cl
WGK Germany	3
PubChem CID	107992
Molecular Weight	103.12

PubChem CID

CAS Registry No.

ChEMBL Ligand

BindingDB Ligand

Wikipedia

GPCRdb Ligand

Solubility

Soluble in water (50 mM), and DMSO (≥20 mg/ml).

Refractive Index

n20D1.57 (Predicted)

Boil Point(°C)

364.1° C at 760 mmHg (Predicted)

Melt Point(°C)

300° C (dec.)

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