MK-499 , CAS No.M611915, Channel blocker of K v10.1

Item Number

M611915

Grouped product items
SKU	Size	Availability	Price	Qty
M611915-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,300.90
M611915-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

Basic Description

Synonyms	MK-499\|MK 499\|MK-499 free base\|OM3KJ27ATS\|L-706000 free base\|UNII-OM3KJ27ATS\|L 706000\|8NWU765OLC\|L-706,000\|L-706000\|150481-98-4\|161799-18-4\|Methanesulfonamide, N-(1'-(6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl)-3,4-dihydro-4-hydroxyspiro(2H-1-benzopyran-2,
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of K v10.1

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydronaphthalen-2-yl]-4-hydroxyspiro[chroman-2,4'-piperidine]-6-yl]methanesulfonamide
INCHI	InChI=1S/C25H29N3O4S/c1-33(30,31)27-20-5-7-24-22(14-20)23(29)15-25(32-24)8-10-28(11-9-25)21-6-4-18-12-17(16-26)2-3-19(18)13-21/h2-3,5,7,12,14,21,23,27,29H,4,6,8-11,13,15H2,1H3/t21-,23-/m1/s1
InChi Key	NIYGLRKUBPNXQS-FYYLOGMGSA-N
Canonical SMILES	N#Cc1ccc2c(c1)CC[C@H](C2)N1CCC2(CC1)C[C@@H](O)c1c(O2)ccc(c1)NS(=O)(=O)C
Isomeric SMILES	CS(=O)(=O)NC1=CC2=C(C=C1)OC3(CCN(CC3)[C@@H]4CCC5=C(C4)C=CC(=C5)C#N)C[C@H]2O
PubChem CID	9934294

PubChem CID

ChEMBL Ligand

BindingDB Ligand

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description