ML 297 - ≥99%(HPLC), high purity , CAS No.1443246-62-5, Activator of K ir3.1

Item Number

M288365

• Synonyms: N-(3,4-Difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea；ML297；N-(3,4-difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-urea；VU 0456810； CID 56642816；CID 56642816； VU0456810；1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea；
• Specifications & Purity: Moligand™, ≥99%(HPLC)
• Biochemical and Physiological Mechanisms: Selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). Exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels,
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ACTIVATOR
• Mechanism of action: Activator of K ir3.1