Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M288647-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
M288647-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
M288647-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $448.90 | |
M288647-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $817.90 |
Selective negative allosteric modulator of group II mGlu receptors
Synonyms | 4-(8-Bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)-2-pyridinecarbonitrile;4-(7-bromo-4-hydroxy-3H-benzo[b][1,4]diazepin-2-yl)picolinonitrile |
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Specifications & Purity | ≥98%(HPLC) |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR |
Mechanism of action | Allosteric modulator of mGlu 2 receptor;Allosteric modulator of mGlu 3 receptor |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 4-(8-bromo-2-oxo-1,3-dihydro-1,5-benzodiazepin-4-yl)pyridine-2-carbonitrile |
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INCHI | InChI=1S/C15H9BrN4O/c16-10-1-2-12-14(6-10)20-15(21)7-13(19-12)9-3-4-18-11(5-9)8-17/h1-6H,7H2,(H,20,21) |
InChi Key | KMKZCMKOSAKVGY-UHFFFAOYSA-N |
Canonical SMILES | C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N |
Isomeric SMILES | C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N |
PubChem CID | 25210562 |
Molecular Weight | 341.16 |
CAS Registry No. | 946619-21-2 |
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PubChem CID | 73755193 |
GPCRdb Ligand | MNI-137 |
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Solubility | Solvent:DMSO, Max Conc. mg/mL: 17.06, Max Conc. mM: 50 |
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