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MNI 137 - ≥98%(HPLC), high purity , CAS No.946619-21-2, Allosteric modulator of mGlu 2 receptor;Allosteric modulator of mGlu 3 receptor

  • Moligand™
  • ≥98%(HPLC)
Item Number
M288647
Grouped product items
SKUSizeAvailabilityPrice Qty
M288647-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
M288647-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
M288647-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$448.90
M288647-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$817.90

Selective negative allosteric modulator of group II mGlu receptors

Basic Description

Synonyms4-(8-Bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)-2-pyridinecarbonitrile;4-(7-bromo-4-hydroxy-3H-benzo[b][1,4]diazepin-2-yl)picolinonitrile
Specifications & Purity≥98%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of mGlu 2 receptor;Allosteric modulator of mGlu 3 receptor

Associated Targets

GRM2 Tchem Metabotropic glutamate receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM3 Tchem Metabotropic glutamate receptor 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 4-(8-bromo-2-oxo-1,3-dihydro-1,5-benzodiazepin-4-yl)pyridine-2-carbonitrile
INCHI InChI=1S/C15H9BrN4O/c16-10-1-2-12-14(6-10)20-15(21)7-13(19-12)9-3-4-18-11(5-9)8-17/h1-6H,7H2,(H,20,21)
InChi Key KMKZCMKOSAKVGY-UHFFFAOYSA-N
Canonical SMILES C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N
Isomeric SMILES C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N
PubChem CID 25210562
Molecular Weight 341.16

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 17.06, Max Conc. mM: 50

Related Documents

Solution Calculators