Monastrol - 98%, high purity , CAS No.329689-23-8

Item Number

M274759

Grouped product items
SKU	Size	Availability	Price
M274759-10mg	10mg	In stock	$118.90
M274759-50mg	50mg	In stock	$423.90
M274759-250mg	250mg	In stock	$1,908.90
M274759-1g	1g	In stock	$6,868.90

Potent and cell permeable mitosis inhibitor. Kinesin Eg5 inhibitor.

Basic Description

Synonyms	monastrol\|329689-23-8\|254753-54-3\|DL-Monastrol\|ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE\|(S)-Monastrol\|(+/-)-Monastrol\|4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Eth
Specifications & Purity	98%
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Dry ice
Product Description	Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.

Names and Identifiers

Pubchem Sid	488194127
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488194127
IUPAC Name	ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate
INCHI	InChI=1S/C14H16N2O3S/c1-3-19-13(18)11-8(2)15-14(20)16-12(11)9-5-4-6-10(17)7-9/h4-7,12,17H,3H2,1-2H3,(H2,15,16,20)
InChi Key	LOBCDGHHHHGHFA-UHFFFAOYSA-N
Canonical SMILES	CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
Isomeric SMILES	CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
PubChem CID	2987927
Molecular Weight	292.35

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
B2320412	Certificate of Analysis	Mar 07, 2024	M274759
B2320411	Certificate of Analysis	Mar 07, 2024	M274759
B2320380	Certificate of Analysis	Feb 01, 2024	M274759
C2308889	Certificate of Analysis	Dec 18, 2023	M274759
C2308890	Certificate of Analysis	Dec 18, 2023	M274759
C2308897	Certificate of Analysis	Dec 18, 2023	M274759
B2320418	Certificate of Analysis	Dec 18, 2023	M274759
B2320419	Certificate of Analysis	Dec 18, 2023	M274759
B2320420	Certificate of Analysis	Dec 18, 2023	M274759
B2320427	Certificate of Analysis	Dec 18, 2023	M274759

Solubility

Soluble in DMSO to 100 mM and in ethanol to 100 mM

Sensitivity

light sensitive

References

1. Cho YC et al.. (2015) Cell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1.. Cell Death Differ, 22 (10): (1605-17). [PMID:25633196]
2. Walton CC et al.. (2019) Primary neurons can enter M-phase.. Sci Rep, 9 (4594). [PMID:30872646]

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Basic Description