Montelukast Dicyclohexylamine Salt is an analogue of Montelukast , a selective CysLT|1|receptor antagonist, which blocks leukotriene D4 (LTD4) and secondary ligands such as LTC4 and LTE4 from binding to the receptor. Studies indicate that LTD4 functions biologically by increasing bronchoconstriction, microvascular permeability, and are vasoconstriction of coronary arteries. It is known that inhibition of leukotriene D4 is competitive. Leukotriene D4 is such as important biochemical mediator in various biochemical pathways, so Montelukast Dicyclohexylamine Salt is a useful tool in regulating these pathways. Furthermore, studies on rat colitis indicate that Montelukast Dicyclohexylamine Salt can reduce the expression of COX-2 and amplify the production of PGE2 (Prostaglandin E2 - sc-201225).