Mosloflavone - 99%, high purity , CAS No.740-33-0

Item Number

M647485

Grouped product items
SKU	Size	Availability	Price
M647485-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$183.90
M647485-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$403.90
M647485-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$686.90

Flavonoids Flavones Phenols Monophenols

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Basic Description

Synonyms	Mosloflavone\|740-33-0\|5-Hydroxy-6,7-dimethoxyflavone\|5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one\|5-hydroxy-6,7-dimethoxy-2-phenylchromen-4-one\|5-HYDROXY-6,7-DIMETHOXYLFLAVONE\|4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-phenyl-\|F4DL1FN60Q\|UNII-F
Specifications & Purity	99%
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with anti-EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation. In Vitro Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC 50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: EV71,bacterial

Names and Identifiers

IUPAC Name	5-hydroxy-6,7-dimethoxy-2-phenylchromen-4-one
INCHI	InChI=1S/C17H14O5/c1-20-14-9-13-15(16(19)17(14)21-2)11(18)8-12(22-13)10-6-4-3-5-7-10/h3-9,19H,1-2H3
InChi Key	SIVAITYPYQQYAP-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
Isomeric SMILES	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
PubChem CID	471722
Molecular Weight	298.29

Solubility

DMSO : 50 mg/mL (167.62 mM; Need ultrasonic)

Flash Point(°F)

Not applicable

Flash Point(°C)

Not applicable

Solution Calculators

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Basic Description