| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| M638944-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $779.90 |
MPBH
| Storage Temp | Store at 2-8°C,Desiccated |
|---|---|
| Shipped In | Wet ice |
| Product Description | Product introduction： MPBH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates). Features of MPBH: • Reactive groups:maleimide andhydrazide • Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups • Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable) • Maleimide group reacts with sulfhydryl groups to form stable thioether linkages • Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates • Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups • Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups Product References: Crosslinker Application Guide -- search for recent literature references for this product • Reactive Moiety:Amine,Hydrazide,Maleimide • Crosslinker Type:Heterobifunctional • Form:Powder • Spacer:Medium(10 to 30 Å) • Labeling Method:Chemical Labeling • Spacer Arm Length:17.9 Å |
| Reactivity | Carbohydrate-Sulfhydryl |
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| Molecular Weight | 309.75 |
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Enter Lot Number to search for COA:
| Solubility | DMF,DMSO |
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| 1. Gunning AP, Bongaerts RJ, Morris VJ. () Recognition of galactan components of pectin by galectin-3.. FASEB J, [PMID:18832596] |
| 2. Gunning AP, Chambers S, Pin C, Man AL, Morris VJ, Nicoletti C. () Mapping specific adhesive interactions on living human intestinal epithelial cells with atomic force microscopy.. FASEB J, [PMID:18263697] |
