Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC 50 of 50 nM.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Product Description
Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC 50 of 50 nM.
In Vitro
Mps1-IN-3 is a potent MPS1 kinase inhibitor, with an IC 50 of 50 nM. Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells with an IC 50 of appr 5 µM. Mps1-IN-3 (2 μM) can completely abrogates checkpoint. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models, with prolonged survival and no toxicity . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:Mps1 50 nM (IC 50 )
Associated Targets(Human)
TTKTchemDual specificity protein kinase TTK (2978 Activities)
