MQAE [1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide] - ≥97.0%,For fluorescence analysis, high purity , CAS No.162558-52-3

2 Citations

Item Number

M131144

Grouped product items
SKU	Size	Availability	Price
M131144-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$94.90
M131144-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$331.90
M131144-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$597.90

Fluorescent chloride ion indicator

Basic Description

Synonyms	FT-0629283 \| CS-6018 \| Quinolinium, 1-(2-ethoxy-2-oxoethyl)-6-methoxy-, bromide (1:1) \| SB73053 \| 1-(2-Ethoxy-2-oxoethyl)-6-methoxyquinolin-1-ium bromide \| 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide \| SCHEMBL223614 \| MQAE \| Quinolinium,1-(2-eth
Specifications & Purity	≥97.0%,For fluorescence analysis
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Grade	for fluorescence analysis
Product Description	MQAE is a fluorescent chloride ion indicator that is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is a fluorescent indicator that is quenched via collision with chloride. 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide, a fluorescent chloride indicator dye, may be used to measure intracellular and extracellular chloride concentrations.

Names and Identifiers

IUPAC Name	ethyl 2-(6-methoxyquinolin-1-ium-1-yl)acetate;bromide
INCHI	InChI=1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1
InChi Key	DSLLHVISNOIYHR-UHFFFAOYSA-M
Canonical SMILES	CCOC(=O)C[N+]1=CC=CC2=C1C=CC(=C2)OC.[Br-]
Isomeric SMILES	CCOC(=O)C[N+]1=CC=CC2=C1C=CC(=C2)OC.[Br-]
WGK Germany	3
PubChem CID	2762651
Molecular Weight	326.186

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
F2220237	Certificate of Analysis	Apr 02, 2024	M131144
F2220238	Certificate of Analysis	Apr 02, 2024	M131144
F2220239	Certificate of Analysis	Apr 02, 2024	M131144
K2104115	Certificate of Analysis	Aug 07, 2023	M131144
K2104175	Certificate of Analysis	Aug 07, 2023	M131144

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3

Citations of This Product

1. Sun Weijia, Li Yuheng, Li Jianwei, Tan Yingjun, Yuan Xinxin, Meng Haoye, Ye Jianting, Zhong Guohui, Jin XiaoYan, Liu Zizhong, Du Ruikai, Xing Wenjuan, Zhao Dingsheng, Song Jinping, Li Youyou, Pan Junjie, Zhao Yunzhang, Li Qi, Wang Aiyuan, Ling Shukuan, Dai Rongji, Li Yingxian. (2023) Mechanical stimulation controls osteoclast function through the regulation of Ca2+-activated Cl− channel Anoctamin 1. Communications Biology, 6 (1): (1-13). [PMID:37055517]
2. Xi-Hui Yu,Xiao-Qiao Hong,Wen-Hua Chen. (2019-01-30) Fluorinated bisbenzimidazoles: a new class of drug-like anion transporters with chloride-mediated, cell apoptosis-inducing activity.. Organic & biomolecular chemistry, 17 ((6)): (1558-1571). [PMID:30694281]

References

1. Huang W et al.. (2020) Increased intracellular Cl- concentration improves airway epithelial migration by activating the RhoA/ROCK Pathway.. Theranostics, 10 (19): (8528-8540). [PMID:32754261]
2. Kaneko Y et al.. (2016) Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro.. Sci Rep, 6 (35659). [PMID:27767042]
3. Pampaloni NP et al.. (2018) Single-layer graphene modulates neuronal communication and augments membrane ion currents.. Nat Nanotechnol, 13 (8): (755-764). [PMID:29892019]
4. Sun Weijia, Li Yuheng, Li Jianwei, Tan Yingjun, Yuan Xinxin, Meng Haoye, Ye Jianting, Zhong Guohui, Jin XiaoYan, Liu Zizhong, Du Ruikai, Xing Wenjuan, Zhao Dingsheng, Song Jinping, Li Youyou, Pan Junjie, Zhao Yunzhang, Li Qi, Wang Aiyuan, Ling Shukuan, Dai Rongji, Li Yingxian. (2023) Mechanical stimulation controls osteoclast function through the regulation of Ca2+-activated Cl− channel Anoctamin 1. Communications Biology, 6 (1): (1-13). [PMID:37055517]
5. Xi-Hui Yu,Xiao-Qiao Hong,Wen-Hua Chen. (2019-01-30) Fluorinated bisbenzimidazoles: a new class of drug-like anion transporters with chloride-mediated, cell apoptosis-inducing activity.. Organic & biomolecular chemistry, 17 ((6)): (1558-1571). [PMID:30694281]

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Basic Description