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MSA 2 - ≥98%(HPLC), high purity , CAS No.129425-81-6

≥98%(HPLC)

CAS#: 129425-81-6
Formula: C₁₄H₁₄O₅S
Molecular Weight: 294.32
PubChem CID: 23035251

Item Number

M288436

Grouped product items
SKU	Size	Availability	Price
M288436-10mg	10mg	In stock	$29.90
M288436-50mg	50mg	In stock	$89.90
M288436-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
M288436-250mg	250mg	In stock	$769.90
M288436-1g	1g	In stock	$1,999.90

Non-nucleotide STING agonist

View related series

Immunology/Inflammation STING

Basic Description

Synonyms	MSA-2\|129425-81-6\|4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid\|4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid\|MSA2\|MSA 2\|SCHEMBL9208326\|CHEMBL4434776\|APCLRHPWFCQIMG-UHFFFAOYSA-N\|BDBM453551\|EX-A4363\|US10730849, Example 16\|NSC828583\|
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Non-nucleotide STING agonist (EC50values are 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively). Exhibits antitumor activity and stimulates interferon-β secretion in tumors. Induces tumor regression with durable antitumor immunity, and syner
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid
INCHI	InChI=1S/C14H14O5S/c1-18-10-5-8-6-13(9(15)3-4-14(16)17)20-12(8)7-11(10)19-2/h5-7H,3-4H2,1-2H3,(H,16,17)
InChi Key	APCLRHPWFCQIMG-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=C2C(=C1)C=C(S2)C(=O)CCC(=O)O)OC
Isomeric SMILES	COC1=C(C=C2C(=C1)C=C(S2)C(=O)CCC(=O)O)OC
PubChem CID	23035251
Molecular Weight	294.32

Certificates

Certificate of Analysis(COA)

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15 results found

Lot Number	Certificate Type	Date	Item
G2429592	Certificate of Analysis	Jun 18, 2024	M288436
G2429593	Certificate of Analysis	Jun 18, 2024	M288436
G2429594	Certificate of Analysis	Jun 18, 2024	M288436
G2429595	Certificate of Analysis	Jun 18, 2024	M288436
G2429596	Certificate of Analysis	Jun 18, 2024	M288436
A2416075	Certificate of Analysis	Jul 12, 2022	M288436
K2209796	Certificate of Analysis	Jul 12, 2022	M288436
K2209818	Certificate of Analysis	Jul 12, 2022	M288436
K2209828	Certificate of Analysis	Jul 12, 2022	M288436
K2209846	Certificate of Analysis	Jul 12, 2022	M288436
L2325020	Certificate of Analysis	Jul 12, 2022	M288436
B2216005	Certificate of Analysis	Jan 10, 2022	M288436
B2216006	Certificate of Analysis	Jan 10, 2022	M288436
B2216007	Certificate of Analysis	Jan 10, 2022	M288436
B2216009	Certificate of Analysis	Jan 10, 2022	M288436

Solubility

Solvent:DMSO, Max Conc. mg/mL: 29.43, Max Conc. mM: 100

Sensitivity

light sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

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