Click Here for 5% Off Your First Aladdin Purchase!

MSC 2032964A - ≥98%(HPLC), high purity , CAS No.1124381-43-6, Inhibitor of mitogen-activated protein kinase kinase kinase 5

  • Moligand™
  • ≥98%(HPLC)
Item Number
M287311
Grouped product items
SKUSizeAvailabilityPrice Qty
M287311-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$136.90
M287311-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$209.90
M287311-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$472.90
M287311-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$820.90

Potent and selective ASK1 inhibitor

Basic Description

Synonyms1124381-43-6|MSC2032964A|MSC 2032964A|MSC-2032964A|N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide|U7AP46TK3Q|CHEMBL3330170|N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridi
Specifications & Purity≥98%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of mitogen-activated protein kinase kinase kinase 5

Associated Targets

MAP3K5 Tchem Mitogen-activated protein kinase kinase kinase 5 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]pyridine-3-carboxamide
INCHI InChI=1S/C16H13F3N6O/c17-16(18,19)10-6-12(21-11-3-4-11)25-13(7-10)22-15(24-25)23-14(26)9-2-1-5-20-8-9/h1-2,5-8,11,21H,3-4H2,(H,23,24,26)
InChi Key XUKGFHHTSUKORV-UHFFFAOYSA-N
Canonical SMILES C1CC1NC2=CC(=CC3=NC(=NN23)NC(=O)C4=CN=CC=C4)C(F)(F)F
Isomeric SMILES C1CC1NC2=CC(=CC3=NC(=NN23)NC(=O)C4=CN=CC=C4)C(F)(F)F
Alternate CAS 1124381-43-6
PubChem CID 25214468
Molecular Weight 362.31

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 7.25, Max Conc. mM: 20; Solvent:ethanol, Max Conc. mg/mL: 3.62, Max Conc. mM: 10 with gentle warming

Related Documents

References

1. Guo X, Harada C, Namekata K, Matsuzawa A, Camps M, Ji H, Swinnen D, Jorand-Lebrun C, Muzerelle M, Vitte PA et al..  (2010)  Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway..  EMBO Mol Med,  (12): (504-15).  [PMID:21064192]

Solution Calculators