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STE:Homologs of yeast Sterile 7, Sterile 11, Sterile 20 kinases
MSC2032964A , CAS No.M612095, Inhibitor of mitogen-activated protein kinase kinase kinase 5

MSC2032964A , CAS No.M612095, Inhibitor of mitogen-activated protein kinase kinase kinase 5

Item Number

M612095

Grouped product items
SKU	Size	Availability	Price	Qty
M612095-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
M612095-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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Basic Description

Synonyms	1124381-43-6\|MSC2032964A\|MSC 2032964A\|MSC-2032964A\|N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide\|U7AP46TK3Q\|CHEMBL3330170\|N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridi
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of mitogen-activated protein kinase kinase kinase 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
INCHI	InChI=1S/C16H13F3N6O/c17-16(18,19)10-6-12(21-11-3-4-11)25-13(7-10)22-15(24-25)23-14(26)9-2-1-5-20-8-9/h1-2,5-8,11,21H,3-4H2,(H,23,24,26)
InChi Key	XUKGFHHTSUKORV-UHFFFAOYSA-N
Canonical SMILES	O=C(c1cccnc1)Nc1nn2c(n1)cc(cc2NC1CC1)C(F)(F)F
Isomeric SMILES	C1CC1NC2=CC(=CC3=NC(=NN23)NC(=O)C4=CN=CC=C4)C(F)(F)F
PubChem CID	25214468

PubChem CID	25214468

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1. Guo X, Harada C, Namekata K, Matsuzawa A, Camps M, Ji H, Swinnen D, Jorand-Lebrun C, Muzerelle M, Vitte PA et al.. (2010) Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway.. EMBO Mol Med, 2 (12): (504-15). [PMID:21064192]

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