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MSDH-C , CAS No.144474-37-3
a potent inhibitor of glycosphingolipid biosynthesis
Basic Description
Synonyms | MSDH-C | 144474-37-3 | N-[(2R,3R)-3-hydroxy-1-methylsulfanylnonan-2-yl]dodecanamide | (2R,3R)-(2-N-Lauroyl)-amino-1-methylthio-3-hydroxynonan | Dodecanamide, N-[(1R,2R)-2-hydroxy-1-[(methylthio)methyl]octyl]- | DTXSID30433983 | D-erythro-1-Methylthiohydroceramide | J-0 |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | MSDH-C is a potent inhibitor of glycosphingolipid biosynthesis. At 10 μM decreases|de novo|ceramide biosynthesis by about 90%. |
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Names and Identifiers
IUPAC Name | N-[(2R,3R)-3-hydroxy-1-methylsulfanylnonan-2-yl]dodecanamide |
INCHI | InChI=1S/C22H45NO2S/c1-4-6-8-10-11-12-13-14-16-18-22(25)23-20(19-26-3)21(24)17-15-9-7-5-2/h20-21,24H,4-19H2,1-3H3,(H,23,25)/t20-,21+/m0/s1 |
InChi Key | FWXRYYWKKSLFEH-LEWJYISDSA-N |
Canonical SMILES | CCCCCCCCCCCC(=O)NC(CSC)C(CCCCCC)O |
Isomeric SMILES | CCCCCCCCCCCC(=O)N[C@@H](CSC)[C@@H](CCCCCC)O |
PubChem CID | 10000297 |
Molecular Weight | 387.66 |
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Chemical and Physical Properties
Solubility | Soluble in DMSO or methanol. |
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