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CAMK:Calcium/calmodulin-dependent protein kinases
MT47-100 , CAS No.M612101, Activator of protein kinase AMP-activated non-catalytic subunit beta 1;Allosteric modulator of protein kinase AMP-activated non-catalytic subunit beta 2

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MT47-100 , CAS No.M612101, Activator of protein kinase AMP-activated non-catalytic subunit beta 1;Allosteric modulator of protein kinase AMP-activated non-catalytic subunit beta 2

Moligand™

PubChem CID: 91938093

Item Number

M612101

Grouped product items
SKU	Size	Availability	Price	Qty
M612101-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
M612101-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

protein kinase AMP-activated non-catalytic subunit beta 1 Activator protein kinase AMP-activated non-catalytic subunit beta 2 Allosteric modulator

Basic Description

Grade	Moligand™
Action Type	ACTIVATOR, ALLOSTERIC MODULATOR
Mechanism of action	Activator of protein kinase AMP-activated non-catalytic subunit beta 1;Allosteric modulator of protein kinase AMP-activated non-catalytic subunit beta 2

Associated Targets

PRKAB2 Tchem 5'-AMP-activated protein kinase subunit beta-2 1 Activities

Discover Target: PRKAB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PRKAB1 Tchem 5'-AMP-activated protein kinase subunit beta-1 1 Activities

Discover Target: PRKAB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	6-[4-(2-hydroxyphenyl)phenyl]quinoline-2,3,4-triol
INCHI	InChI=1S/C21H15NO4/c23-18-4-2-1-3-15(18)13-7-5-12(6-8-13)14-9-10-17-16(11-14)19(24)20(25)21(26)22-17/h1-11,23,25H,(H2,22,24,26)
InChi Key	DMDAXRKDNRQTIF-UHFFFAOYSA-N
Canonical SMILES	Oc1ccccc1c1ccc(cc1)c1ccc2c(c1)c(O)c(c(n2)O)O
Isomeric SMILES	C1=CC=C(C(=C1)C2=CC=C(C=C2)C3=CC4=C(C=C3)NC(=O)C(=C4O)O)O
PubChem CID	91938093

Database links

PubChem CID	91938093

Certificates

Certificate of Analysis(COA)

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References

1. Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE et al.. (2015) Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.. Chem Biol, 22 (6): (705-11). [PMID:26091167]

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