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mTOR Inhibitor-1 - 98%, high purity , CAS No.468747-17-3
Basic Description Specifications & Purity ≥98% Biochemical and Physiological Mechanisms The addition of C-4 (mTOR inhibitor-1, 0~12.8 μg/ml) directly decreases the level of activated mTOR (p-mTORser2448) which is phosphorylated at Ser2448. The proliferation of A549 cells is strongly inhibited by C-4, and the inhibitory effect is time- and do Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads
Names and Identifiers IUPAC Name 3-bromo-N-[1-(2,4-dihydroxyphenyl)ethylideneamino]-4-methylbenzamide INCHI InChI=1S/C16H15BrN2O3/c1-9-3-4-11(7-14(9)17)16(22)19-18-10(2)13-6-5-12(20)8-15(13)21/h3-8,20-21H,1-2H3,(H,19,22) InChi Key NKMSVTGHOVMMHV-UHFFFAOYSA-N Canonical SMILES CC1=C(C=C(C=C1)C(=O)NN=C(C)C2=C(C=C(C=C2)O)O)Br Isomeric SMILES CC1=C(C=C(C=C1)C(=O)NN=C(C)C2=C(C=C(C=C2)O)O)Br PubChem CID 1013573 Molecular Weight 363.21 Reaxy-Rn 33612622
Chemical and Physical Properties Solubility ≥41.9 mg/mL in DMSO Sensitivity Air Sensitive,Heat Sensitive Melt Point(°C) 262 °C
Safety and Hazards(GHS) Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H302: Harmful if swallowed
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P301+P312: IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.
Reaxy-Rn 33612622
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