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Myosin V-IN-1 , CAS No.1259177-59-7

Item Number
M650495
Grouped product items
SKUSizeAvailabilityPrice Qty
M650495-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$333.90
M650495-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90
M650495-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$690.90
View related series
Cytoskeleton Myosin

Basic Description

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Myosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a K i of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex.

In Vitro

Myosin V-IN-1 (compound 8) shows dose-dependent reduction of the rate of steady-state actin-activated ATP hydrolysis by single-headed myosin V. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

Canonical SMILES O=C(C1=CC(SCC2=CC(NC3=NC(NN=C4C5=CC=C(N6CCOCC6)C=C5)=C4C=N3)=CC=C2)=CC=C1)O
Molecular Weight 538.62

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (185.66 mM; Need ultrasonic)

Related Documents

Solution Calculators