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Basic Description
| Synonyms | Tetradecanoic acid|MYRISTIC ACID|544-63-8|n-Tetradecanoic acid|Crodacid|n-Tetradecan-1-oic acid|n-Tetradecoic acid|1-Tridecanecarboxylic acid|Myristate|Hydrofol acid 1495|Myristinsaeure|Univol U 316S|Emery 655|tetradecoic acid|Hystrene 9014|Myristic acid, |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Product Description | Myristic acid is a straight-chain 14-carbon fatty acid. Diets rich in myristic acid, along with lauric and palmitic acids, are associated with increased serum levels of low densisity lipoprotein cholesterol. |
Associated Targets
GPR84 Tchem G-protein coupled receptor 84 0 Activities
DNM1 Tbio Dynamin-1 0 Activities
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CBX1 Tbio Chromobox protein homolog 1 0 Activities
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GMNN Tbio Geminin 0 Activities
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RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 0 Activities
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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities
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VDR Tclin Vitamin D3 receptor 0 Activities
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FFAR4 Tchem Free fatty acid receptor 4 1 Activities
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FEN1 Tchem Flap endonuclease 1 0 Activities
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KAT2A Tchem Histone acetyltransferase KAT2A 0 Activities
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TLR2 Tchem Toll-like receptor 2 0 Activities
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SIRT6 Tchem NAD-dependent protein deacetylase sirtuin-6 0 Activities
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UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 0 Activities
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UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 0 Activities
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TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 0 Activities
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PLK1 Tchem Serine/threonine-protein kinase PLK1 0 Activities
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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities
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PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities
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ALOX15B Tchem Arachidonate 15-lipoxygenase B 0 Activities
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NR1H4 Tclin Bile acid receptor 0 Activities
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CYP19A1 Tclin Aromatase 0 Activities
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities
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ACHE Tclin Acetylcholinesterase 0 Activities
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TARDBP Tchem TAR DNA-binding protein 43 0 Activities
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SMPD1 Tchem Sphingomyelin phosphodiesterase 0 Activities
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BCHE Tclin Cholinesterase 0 Activities
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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities
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PPARA Tclin Peroxisome proliferator-activated receptor alpha 0 Activities
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PPARD Tchem Peroxisome proliferator-activated receptor delta 0 Activities
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PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities
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Names and Identifiers
| IUPAC Name | tetradecanoic acid |
|---|---|
| INCHI | InChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16) |
| InChi Key | TUNFSRHWOTWDNC-UHFFFAOYSA-N |
| Canonical SMILES | CCCCCCCCCCCCCC(=O)O |
| Isomeric SMILES | CCCCCCCCCCCCCC(=O)O |
| RTECS | QH4375000 |
| PubChem CID | 11005 |
| Molecular Weight | 228.37 |
| Beilstein | 508624 |
| Reaxy-Rn | 508624 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Sensitivity | Moisture sensitive. |
|---|---|
| Refractive Index | 1.4273 |
| Flash Point(°F) | >235.4 °F |
| Flash Point(°C) | >113 °C |
| Boil Point(°C) | 326°C |
| Melt Point(°C) | 50-57°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS09, GHS05, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects H413:May cause long lasting harmful effects to aquatic life H318:Causes serious eye damage H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
| RTECS | QH4375000 |
| Reaxy-Rn | 508624 |
| Merck Index | 6333 |