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Lipid modifying kinases
N-[(2S)-1-hydroxypropan-2-yl]-5-[5-(2-hydroxypropan-2-yl)-2-methyl-7-[[3-(1-methylimidazol-2-yl)phenyl]methylamino]pyrazolo[1,5-a]pyrimidin-3-yl]-N,2-dimethylbenzamide , CAS No.N608959, Inhibitor of phosphatidylinositol 4-kinase beta

N-[(2S)-1-hydroxypropan-2-yl]-5-[5-(2-hydroxypropan-2-yl)-2-methyl-7-[[3-(1-methylimidazol-2-yl)phenyl]methylamino]pyrazolo[1,5-a]pyrimidin-3-yl]-N,2-dimethylbenzamide , CAS No.N608959, Inhibitor of phosphatidylinositol 4-kinase beta

Item Number

N608959

Grouped product items
SKU	Size	Availability	Price	Qty
N608959-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
N608959-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 22
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of phosphatidylinositol 4-kinase beta

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

INCHI	InChI=1S/C33H39N7O3/c1-20-11-12-24(16-26(20)32(42)39(7)21(2)19-41)29-22(3)37-40-28(17-27(33(4,5)43)36-31(29)40)35-18-23-9-8-10-25(15-23)30-34-13-14-38(30)6/h8-17,21,35,41,43H,18-19H2,1-7H3/t21-/m0/s1
InChi Key	LGILUCRVDGGDMI-NRFANRHFSA-N
Canonical SMILES	Cc1c(cc(cc1)c1c2nc(cc(n2nc1C)NCc1cc(ccc1)c1nccn1C)C(C)(C)O)C(=O)N(C)[C@@H](C)CO
PubChem CID	139330094

PubChem CID	139330094

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1. Yang N, Ma P, Lang J, Zhang Y, Deng J, Ju X, Zhang G, Jiang C. (2012) Phosphatidylinositol 4-kinase IIIβ is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry.. J Biol Chem, 287 (11): (8457-67). [PMID:22253445]

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