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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N608738-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,334.90 | |
N608738-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Synonyms | compound 15a |
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Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of enhancer of zeste 2 polycomb repressive complex 2 subunit;Inhibitor of nuclear receptor binding SET domain protein 1;Inhibitor of nuclear receptor binding SET domain protein 2 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-(3-((7-Chloro-5,8-dioxo-5,8-dihydroquinolin-6-yl)amino)bicyclo[1.1.1]pentan-1-yl)but-2-ynamide |
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INCHI | InChI=1S/C18H14ClN3O3/c1-2-4-11(23)21-17-7-18(8-17,9-17)22-14-12(19)16(25)13-10(15(14)24)5-3-6-20-13/h3,5-6,22H,7-9H2,1H3,(H,21,23) |
InChi Key | XLARJZRINWFNRT-UHFFFAOYSA-N |
Canonical SMILES | O=C1C(=C(Cl)C(=O)c2ncccc12)NC12CC(C1)(NC(=O)C#CC)C2 |
Enter Lot Number to search for COA:
1. Tang H, Yu A, Xing L, Chen X, Ding H, Yang H, Song Z, Shi Q, Geng M, Huang X et al.. (2023) Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors.. J Med Chem, 66 (2): (1634-1651). [PMID:36642961] |