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Targets
G protein-coupled receptors (GPCRs)
Metabotropic glutamate receptors
N-[4-(1H-pyrazol-4-yl)-1,3-thiazol-2-yl]pyridin-2-amine , CAS No.N609423, Allosteric modulator of mGlu 4 receptor

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N-[4-(1H-pyrazol-4-yl)-1,3-thiazol-2-yl]pyridin-2-amine , CAS No.N609423, Allosteric modulator of mGlu 4 receptor

Moligand™

PubChem CID: 42645487

Item Number

N609423

Grouped product items
SKU	Size	Availability	Price	Qty
N609423-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
N609423-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

mGlu4 receptor Allosteric modulator

Basic Description

Synonyms	compound 7;compound 7
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of mGlu 4 receptor

Associated Targets

GRM4 Tchem Metabotropic glutamate receptor 4 1 Activities

Discover Target: GRM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-[4-(1H-pyrazol-4-yl)-1,3-thiazol-2-yl]pyridin-2-amine
INCHI	InChI=1S/C11H9N5S/c1-2-4-12-10(3-1)16-11-15-9(7-17-11)8-5-13-14-6-8/h1-7H,(H,13,14)(H,12,15,16)
InChi Key	WIILZWDTWZFGNO-UHFFFAOYSA-N
Canonical SMILES	c1ccc(nc1)Nc1scc(n1)c1c[nH]nc1
Isomeric SMILES	C1=CC=NC(=C1)NC2=NC(=CS2)C3=CNN=C3
PubChem CID	42645487

Database links

PubChem CID	42645487
ChEMBL Ligand	CHEMBL1830693
GPCRdb Ligand	compound 7 [PMID: 20638279]

Certificates

Certificate of Analysis(COA)

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References

1. East SP, Gerlach K. (2010) mGluR4 positive allosteric modulators with potential for the treatment of Parkinson's disease: WO09010455.. Expert Opin Ther Pat, 20 (3): (441-5). [PMID:20180624]

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