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N-(4-Carboxy-3-hydroxyphenyl)maleimide - ≥99%, high purity , CAS No.19232-43-0

  • ≥99%
Item Number
C275046
Grouped product items
SKUSizeAvailabilityPrice Qty
C275046-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
C275046-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90

Irreversible LDH isoenzyme inhibitor

View related series
amide Benzene compounds

Basic Description

SynonymsN-(4-Carboxy-3-hydroxyphenyl)maleimide|19232-43-0|4-Maleimidylsalicylic acid|4-MALEIMIDOSALICYLIC ACID|4-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)-2-hydroxybenzoic acid|4-(2,5-dioxopyrrol-1-yl)-2-hydroxybenzoic acid|Benzoic acid, 4-(2,5-dihydro-2,5-dioxo-1H-
Specifications & Purity≥99%
Biochemical and Physiological MechanismsReported to be an irreversible inhibitor of LDH isoenzyme.
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

The applications of N-(4-Carboxy-3-hydroxyphenyl)maleimide extend to the field of scientific research and laboratory experiments, making it an adaptable compound for diverse studies. It serves as a fluorescent probe, facilitating the detection of proteins, enzymes, and nucleic acids. Furthermore, it proves instrumental in the examination of protein-protein interactions, DNA-protein interactions, as well as the exploration of protein structure and function. By binding to proteins, enzymes, and nucleic acids, N-(4-Carboxy-3-hydroxyphenyl)maleimide actively engages with the target molecules. This interaction occurs through the formation of covalent bonds with the amino acid residues of the target molecule. Stabilized by hydrogen bonds and van der Waals forces, the resulting covalent bond enables N-(4-Carboxy-3-hydroxyphenyl)maleimide to function as a fluorescent probe, facilitating the detection of proteins, enzymes, and nucleic acids.

Names and Identifiers

IUPAC Name 4-(2,5-dioxopyrrol-1-yl)-2-hydroxybenzoic acid
INCHI InChI=1S/C11H7NO5/c13-8-5-6(1-2-7(8)11(16)17)12-9(14)3-4-10(12)15/h1-5,13H,(H,16,17)
InChi Key SMSVFCGGVBWUJL-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C(C=C1N2C(=O)C=CC2=O)O)C(=O)O
Isomeric SMILES C1=CC(=C(C=C1N2C(=O)C=CC2=O)O)C(=O)O
PubChem CID 4302
Molecular Weight 233.18

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO
SensitivityMoisture sensitive

Related Documents

Solution Calculators